Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LHCGR | P22888 | 7/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | FSHR | P23945 | 2/20 | 0.48 |
| ▸ | BRAF | P15056 | 7/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5036580 | 0.92 | LHCGR (0.50) | LHCGRTSHRFSHRBRAFPOLB | |
| SCHEMBL4425936 | 0.89 | BRAF (0.58) | BRAFPOLBFAAHKDM4E | |
| SCHEMBL4426367 | 0.84 | LHCGR (0.55) | LHCGRTSHRFSHRBRAFPOLB | |
| SCHEMBL5028901 | 0.83 | LHCGR (0.54) | LHCGRTSHRFSHRBRAFCHRM4 | |
| SCHEMBL5028895 | 0.83 | LHCGR (0.54) | LHCGRTSHRFSHRBRAFCHRM4 | |
| SCHEMBL5026098 | 0.81 | LHCGR (0.62) | LHCGRTSHRFSHRBRAFCHRM4 | |
| SCHEMBL6220667 | 0.81 | LHCGR (0.53) | LHCGRTSHRFSHRBRAF | |
| SCHEMBL4429274 | 0.80 | LHCGR (0.66) | LHCGRTSHRFSHRBRAF | |
| SCHEMBL4425219 | 0.80 | BRAF (0.55) | BRAFPOLBKDM4E | |
| SCHEMBL5026187 | 0.78 | LHCGR (0.52) | LHCGRTSHRFSHRBRAFCHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1886999-A2 | Bicyclic heteroaromatic compound | N.V. Organon (NL) | 2008-02-13 | — | — | EP | disclosed |