Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LHCGR | P22888 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | FSHR | P23945 | 1/20 | 0.47 |
| ▸ | BRAF | P15056 | 5/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5037256 | 0.92 | LHCGR (0.51) | LHCGRTSHRFSHRBRAFPOLB | |
| SCHEMBL4425219 | 0.89 | BRAF (0.55) | BRAFNPC1RAB9ABTKCYP2C9 | |
| SCHEMBL4429274 | 0.89 | LHCGR (0.66) | LHCGRTSHRFSHRBRAFRXFP1 | |
| SCHEMBL4426367 | 0.83 | LHCGR (0.55) | LHCGRTSHRFSHRBRAFPOLB | |
| SCHEMBL5028895 | 0.82 | LHCGR (0.54) | LHCGRTSHRFSHRBRAFRAB9A | |
| SCHEMBL5028901 | 0.82 | LHCGR (0.54) | LHCGRTSHRFSHRBRAFNPC1 | |
| SCHEMBL5026098 | 0.81 | LHCGR (0.62) | LHCGRTSHRFSHRBRAFNPC1 | |
| SCHEMBL6220667 | 0.80 | LHCGR (0.53) | LHCGRTSHRFSHRBRAFNPC1 | |
| SCHEMBL4425936 | 0.80 | BRAF (0.58) | BRAFPOLB | |
| SCHEMBL4428981 | 0.78 | BRAF (0.53) | LHCGRTSHRFSHRBRAFNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1886999-A2 | Bicyclic heteroaromatic compound | N.V. Organon (NL) | 2008-02-13 | — | — | EP | disclosed |