SCHEMBL5037757

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5037763	1.00	PLAU (0.41)	PLAUTPSAB1PRSS1PLGGAA
	SCHEMBL5037326	0.89	PLAU (0.46)	PLAUTPSAB1PRSS1PLGHDAC3
	SCHEMBL5037324	0.89	PLAU (0.46)	PLAUTPSAB1PRSS1PLGHDAC3
	SCHEMBL5037766	0.83	MASP2 (0.46)	GAAMAPTHTTHDAC3HDAC1
	SCHEMBL5043455	0.83	NPC1 (0.38)	PLAUFFAR1
	SCHEMBL5043453	0.83	NPC1 (0.38)	PLAUFFAR1
	SCHEMBL5041098	0.82	PLAU (0.39)	PLAUTSHRALDH1A1
	SCHEMBL5041769	0.82	PLAU (0.39)	PLAUTPSAB1PRSS1PLGGAA
	SCHEMBL5041771	0.82	PLAU (0.39)	PLAUTPSAB1PRSS1PLGGAA
	SCHEMBL5041095	0.82	PLAU (0.39)	PLAUTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.