Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.36 |
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRE | P78334 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4944211 | 0.84 | ANPEP (0.42) | PLA2G10PLA2G2CANPEPENPEPCA1 | |
| SCHEMBL4940083 | 0.84 | ANPEP (0.42) | PLA2G10PLA2G2CANPEPENPEPCA1 | |
| SCHEMBL5038855 | 0.79 | PLA2G2C (0.52) | ALDH1A1PLA2G10PLA2G2C | |
| SCHEMBL10501294 | 0.77 | SLC6A2 (0.38) | ALDH1A1PLA2G10PLA2G2CANPEPENPEP | |
| SCHEMBL10606210 | 0.77 | SLC6A2 (0.38) | ALDH1A1PLA2G10PLA2G2CANPEPENPEP | |
| SCHEMBL4941282 | 0.74 | GABRP (0.44) | ANPEPENPEPCA1CA12CA9 | |
| SCHEMBL4943954 | 0.74 | GABRP (0.44) | ANPEPENPEPCA1CA12CA9 | |
| SCHEMBL4940114 | 0.74 | GABRP (0.44) | ANPEPENPEPCA1CA12CA9 | |
| SCHEMBL27534582 | 0.69 | CA1 (0.39) | CA1CA12CA9CA2 | |
| SCHEMBL14230379 | 0.68 | CA1 (0.44) | PLA2G2CCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339669-B1 | N-ALKYLATED GABA COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | UCB PHARMA SA (BE) | 2008-06-04 | — | — | EP | disclosed |