Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10606210 | 1.00 | SLC6A2 (0.38) | SLC6A2SLC6A4BLMSLC6A3MEN1 | |
| SCHEMBL4940083 | 0.84 | ANPEP (0.42) | TSHRPLA2G2CANPEPENPEPPLA2G10 | |
| SCHEMBL4944211 | 0.84 | ANPEP (0.42) | TSHRPLA2G2CANPEPENPEPPLA2G10 | |
| SCHEMBL4941282 | 0.78 | GABRP (0.44) | TSHRANPEPENPEPGABRPGABRD | |
| SCHEMBL4940114 | 0.78 | GABRP (0.44) | TSHRANPEPENPEPGABRPGABRD | |
| SCHEMBL4943954 | 0.78 | GABRP (0.44) | TSHRANPEPENPEPGABRPGABRD | |
| SCHEMBL5038855 | 0.77 | PLA2G2C (0.52) | MEN1TSHRKMT2APLA2G2CPLA2G10 | |
| SCHEMBL5037774 | 0.77 | ALDH1A1 (0.37) | PLA2G2CANPEPENPEPPLA2G10GABRP | |
| SCHEMBL16628204 | 0.76 | SLC6A2 (0.40) | SLC6A2SLC6A4BLMSLC6A3MEN1 | |
| SCHEMBL27534582 | 0.69 | CA1 (0.39) | BLMTSHRCA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162036-B1 | (S)-ALPHA-ETHYL-2-OXO-1-PYRROLIDINACETAMIDE | U C B, S.A. (BE) | 1989-08-16 | — | — | EP | claimed |