Chlorobenzene

Chlorobenzene

SCHEMBL5038205

ClCCCl.Clc1ccccc1

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.73
CYP1A2 P05177 1/20 0.50
LMNA P02545 3/20 0.44
CYP2A6 P11509 1/20 0.44
SIGMAR1 Q99720 2/20 0.41
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
ORAI1 Q96D31 1/20 0.40
ORAI2 Q96SN7 1/20 0.40
ORAI3 Q9BRQ5 1/20 0.40
TRPV6 Q9H1D0 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.38
MAPT P10636 1/20 0.38
ALDH1A1 P00352 2/20 0.36
TRPA1 O75762 1/20 0.36
MAPK1 P28482 1/20 0.36
GSK3B P49841 1/20 0.36
HIF1A Q16665 1/20 0.36
IDO1 P14902 2/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorobenzene SCHEMBL947510 0.90 TSHR (0.79) TSHRCYP1A2LMNACYP2A6SIGMAR1
Chlorobenzene SCHEMBL1331798 0.86
Chlorobenzene SCHEMBL2168046 0.86 TSHR (1.00) TSHRCYP1A2LMNACYP2A6SIGMAR1
Chlorobenzene SCHEMBL1568605 0.86 TSHR (1.00) TSHRCYP1A2LMNACYP2A6SIGMAR1
Chlorobenzene SCHEMBL11220629 0.86 TSHR (1.00) TSHRCYP1A2LMNACYP2A6SIGMAR1
SCHEMBL24715429 0.86 TSHR (1.00) TSHRCYP1A2LMNACYP2A6SIGMAR1
Chlorobenzene SCHEMBL1330702 0.86
Chlorobenzene SCHEMBL2044 0.86
Chlorobenzene SCHEMBL9721018 0.86 TSHR (1.00) TSHRCYP1A2LMNACYP2A6SIGMAR1
Chlorobenzene SCHEMBL1339852 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117229167-A Preparation method of pesticide intermediate 湖北梦鑫生物医药科技有限责任公司 2023-12-15 CN disclosed
CN-105637038-B Novel compound and composition containing the same 株式会社艾迪科 2019-10-25 CN disclosed
CN-110325590-A Resin combination and resin-formed body 日本瑞翁株式会社 2019-10-11 CN disclosed
CN-110229265-A The fluoro-containing copolymer composition mixed 索尔维特殊聚合物意大利有限公司 2019-09-13 CN disclosed
CN-104918985-B Method for manufacturing sulfone polymer film 索尔维公司 2019-08-09 CN disclosed
CN-110036343-A Water-soluble composition, pattern forming agent, used they solidfied material manufacturing method and solidfied material 株式会社ADEKA 2019-07-19 CN disclosed
CN-107250203-B Resin-formed body, resin film and injection-molded article 日本瑞翁株式会社 2019-04-26 CN disclosed
CN-106574139-B Fluoropolymer composition 索尔维特殊聚合物意大利有限公司 2019-03-22 CN disclosed
CN-108884250-A Compositions and methods for making sulfone polymer membranes 索尔维特殊聚合物意大利有限公司 2018-11-23 CN disclosed
CN-105473666-B Compound and the composition containing the compound 株式会社艾迪科 2018-06-08 CN disclosed
EP-0848699-B1 BENZOCYCLOALKENE COMPOUNDS WITH MELATONINE RECEPTOR BINDING AFFINITY, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2001-10-24 EP disclosed
US-5922771-A MELATONIN RECEPTOR AGONISTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-07-13 US disclosed
EP-0848699-A1 BENZOCYCLOALKENE COMPOUNDS WITH MELATONINE RECEPTOR BINDING AFFINITY, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1998-06-24 EP disclosed
WO-1997005098-A1 BENZOCYCLOALKENE COMPOUNDS WITH MELATONINE RECEPTOR BINDING AFFINITY, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-02-13 WO disclosed
US-5204225-A Depositing actinic radiation sensitive aminoplast and phenoplast containing resin on substrate, baking, exposing to actinic radiation, developing ROHM AND HAAS COMPANY (US) 1993-04-20 US disclosed
EP-0170524-B1 NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1992-07-15 EP disclosed
US-5034304-A Halogenated compositions for negative images ROHM AND HAAS COMPANY (US) 1991-07-23 US disclosed
US-4968698-A FUNGICIDES, ANTIPROTOZOA AGENTS BURROUGHS WELLCOME CO. (US) 1990-11-06 US disclosed
EP-0170524-A2 Nitrogen containing heterocyclic compounds THE WELLCOME FOUNDATION LIMITED (GB) 1986-02-05 EP disclosed
US-4006178-A Process for the manufacture of dicyanovinyl compounds CIBA-GEIGY CORPORATION (US) 1977-02-01 US disclosed