Chlorobenzene

Chlorobenzene

SCHEMBL947510

ClCCl.Clc1ccccc1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.79
CYP1A2 P05177 1/20 0.53
LMNA P02545 3/20 0.47
CYP2A6 P11509 1/20 0.47
SIGMAR1 Q99720 2/20 0.42
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
ORAI1 Q96D31 1/20 0.42
ORAI2 Q96SN7 1/20 0.42
ORAI3 Q9BRQ5 1/20 0.42
TRPV6 Q9H1D0 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.39
MAPT P10636 1/20 0.39
TRPA1 O75762 1/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPK1 P28482 1/20 0.38
GSK3B P49841 1/20 0.38
HIF1A Q16665 1/20 0.38
IDO1 P14902 2/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorobenzene SCHEMBL5038205 0.90 TSHR (0.73) TSHRCYP1A2LMNACYP2A6SIGMAR1
Chlorobenzene SCHEMBL1568605 0.89 TSHR (1.00) TSHRCYP1A2LMNACYP2A6SIGMAR1
Chlorobenzene SCHEMBL2168046 0.89 TSHR (1.00) TSHRCYP1A2LMNACYP2A6SIGMAR1
Chlorobenzene SCHEMBL2044 0.89
Chlorobenzene SCHEMBL11220629 0.89 TSHR (1.00) TSHRCYP1A2LMNACYP2A6SIGMAR1
SCHEMBL24715429 0.89 TSHR (1.00) TSHRCYP1A2LMNACYP2A6SIGMAR1
Chlorobenzene SCHEMBL1330702 0.89
Chlorobenzene SCHEMBL1331798 0.89
Chlorobenzene SCHEMBL9721018 0.89 TSHR (1.00) TSHRCYP1A2LMNACYP2A6SIGMAR1
Chlorobenzene SCHEMBL1339852 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103601671-A Preparation method of iodo trifluoro methyl pyridine SHANGHAI TITAN SCIENCE & TECHNOLOGY CO LTD 2014-02-26 CN claimed
WO-2010060074-A1 PREPARATION OF NILOTINIB AND INTERMEDIATES THEREOF TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2010-05-27 WO claimed
US-5410014-A Reacting low molecular weight polycarbonate of diphenol having chlorocarbonic acid ester group with aliphatic diol BAYER AKTIENGESELLSCHAFT (DE) 1995-04-25 US claimed
EP-3037441-B1 POLYOLEFIN LG CHEMICAL LTD (KR) 2023-11-22 EP disclosed
EP-4255960-A1 PROCESS FOR PREPARING A POLYCARBONATE USING A HALOGENATED DIARYL CARBONATE Covestro Deutschland AG (DE) 2023-10-11 EP disclosed
US-20230209845-A1 ENHANCING THE LIFETIME OF MOLECULAR AND MOLECULAR SALT PHOTOVOLTAICS & LUMINESCENT SOLAR CONCENTRATORS NATIONAL SCIENCE FOUNDATION 2023-06-29 US disclosed
CN-113613865-A Filament for three-dimensional modeling, wound body, and cartridge for three-dimensional printer 三菱化学株式会社 2021-11-05 CN disclosed
US-20200303667-A1 ENHANCING THE LIFETIME OF ORGANIC SALT PHOTOVOLTAICS BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2020-09-24 US disclosed
CN-110316762-A Beta-hydroxy iron oxides compound and ε-iron oxides compound particle and manufacturing method, the manufacturing method of magnetic recording media 富士胶片株式会社 2019-10-11 CN disclosed
CN-110322902-A The manufacturing method of magnetic recording media, ε-type iron oxides compound particle and the manufacturing method of magnetic recording media 富士胶片株式会社 2019-10-11 CN disclosed
WO-2019156482-A1 METHOD FOR PREPARING SUPPORTED HYBRID METALLOCENE CATALYST 주식회사 엘지화학 2019-08-15 WO disclosed
CN-85102876-B Continuous one-step process for synthesizing polycarbonate 化学工业部晨光化工研究院一分院 1988-08-17 CN disclosed
CN-85102769-B one-step method for synthesizing polycarbonate 化学工业部晨光化工研究院一分院 1988-08-10 CN disclosed
CN-85102876-A The serialization of one-step synthesis of polycarbonic ester (one) 1986-09-17 CN disclosed
CN-85102769-A ONE-STEP SYNTHESIS OF POLYCARBONIC ESTER 1986-09-10 CN disclosed
US-4599412-A STABILIZATION BY ADSORPTION OF WATER WITH MOLECULAR SIEVE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-07-08 US disclosed
US-4425456-A FIREPROOFING MOBAY CHEMICAL CORPORATION (US) 1984-01-10 US disclosed
US-4399271-A CONDENSATION WITH A SULFONYLAMIDE COMPOUND MOBAY CHEMICAL CORPORATION (US) 1983-08-16 US disclosed
US-4306055-A Polycarbonates having sulfur-containing phenolic diols incorporated therein MOBAY CHEMICAL CORPORATION (US) 1981-12-15 US disclosed
US-4043980-A Flame retardant polycarbonate having improved critical thickness MOBAY CHEMICAL CORPORATION (US) 1977-08-23 US disclosed