Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.33 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31261583 | 0.80 | KDM4E (0.46) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL2172840 | 0.76 | ALDH1A1 (0.41) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL2680851 | 0.71 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4472112 | 0.67 | SMN1; SMN2 (0.33) | KDM4EALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL12310191 | 0.67 | AR (0.41) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL5045268 | 0.66 | ALDH1A1 (0.39) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL28241231 | 0.66 | ANPEP (0.56) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL8828836 | 0.66 | ANPEP (0.56) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL15416067 | 0.66 | GABRP (0.38) | KDM4EALDH1A1MAPTHIF1ANCOA3 | |
| SCHEMBL13483957 | 0.66 | KDM4E (0.40) | KDM4EALDH1A1GAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019401-B1 | COMPLEX COMPRISING A RARE-EARTH METAL ION AND A COMPLEXING MOIETY | KONINKL PHILIPS ELECTRONICS NV (NL) | 2008-01-16 | — | — | EP | disclosed |