Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | TEK | Q02763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6481602 | 0.92 | RAB9A (0.45) | RAB9ANPC1MAPTTP53LMNA | |
| SCHEMBL5048567 | 0.90 | NPC1 (0.44) | RAB9ANPC1MAPTTP53LMNA | |
| SCHEMBL5048341 | 0.90 | NPC1 (0.43) | RAB9ANPC1MAPTTP53LMNA | |
| SCHEMBL5039007 | 0.88 | NPC1 (0.42) | RAB9ANPC1MAPTTP53LMNA | |
| SCHEMBL5039260 | 0.87 | LMNA (0.42) | RAB9ANPC1MAPTTP53LMNA | |
| SCHEMBL5039245 | 0.86 | NPC1 (0.42) | RAB9ANPC1MAPTTP53LMNA | |
| SCHEMBL5047148 | 0.86 | NPC1 (0.42) | RAB9ANPC1MAPTTP53LMNA | |
| SCHEMBL5436637 | 0.86 | CSNK1D (0.43) | RAB9ANPC1MAPTTP53LMNA | |
| SCHEMBL1306719 | 0.85 | CSNK1D (0.47) | RAB9ANPC1MAPTTP53LMNA | |
| SCHEMBL5043962 | 0.85 | RAB9A (0.44) | RAB9ANPC1MAPTTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470712-B2 | Amino-benzazoles as P2Y1 receptor inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-30 | — | — | US | claimed |