Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 7/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5041108 | 0.91 | NAAA (0.59) | NAAATMEM97SIGMAR1L3MBTL1HDAC3 | |
| SCHEMBL5046504 | 0.90 | NAAA (0.57) | NAAATMEM97SIGMAR1L3MBTL1HDAC3 | |
| SCHEMBL5045814 | 0.89 | NAAA (0.56) | NAAATMEM97SIGMAR1L3MBTL1HDAC3 | |
| SCHEMBL1854830 | 0.87 | NAAA (0.53) | NAAATMEM97SIGMAR1L3MBTL1HDAC3 | |
| SCHEMBL5045561 | 0.86 | NAAA (0.60) | NAAATMEM97SIGMAR1L3MBTL1HDAC3 | |
| SCHEMBL1856769 | 0.80 | NAAA (0.55) | NAAATMEM97SIGMAR1L3MBTL1HDAC3 | |
| SCHEMBL4325130 | 0.80 | NAAA (0.55) | NAAATMEM97SIGMAR1L3MBTL1HDAC3 | |
| SCHEMBL4315301 | 0.80 | NAAA (0.55) | NAAATMEM97SIGMAR1L3MBTL1HDAC3 | |
| SCHEMBL1856856 | 0.79 | NAAA (0.54) | NAAATMEM97SIGMAR1L3MBTL1HDAC3 | |
| SCHEMBL1853317 | 0.78 | NAAA (0.66) | NAAATMEM97SIGMAR1L3MBTL1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |