SCHEMBL504028

SCHEMBL504028

O=C(O)C1CC[C@H]2CCC[C@@H]12

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 3/20 0.39
SLC1A1 P43005 3/20 0.39
GABRR1 P24046 5/20 0.39
PEPD P12955 1/20 0.38
MEN1 O00255 1/20 0.34
BLM P54132 1/20 0.34
KMT2A Q03164 1/20 0.34
GABRR2 P28476 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2277633 1.00 SLC1A2 (0.39) SLC1A2SLC1A1GABRR1PEPDMEN1
SCHEMBL504027 1.00 SLC1A2 (0.39) SLC1A2SLC1A1GABRR1PEPDMEN1
SCHEMBL11597749 1.00 SLC1A2 (0.39) SLC1A2SLC1A1GABRR1PEPDMEN1
SCHEMBL9019456 0.95 SLC1A2 (0.39) SLC1A2SLC1A1GABRR1MEN1BLM
SCHEMBL19733794 0.93 HSD11B1 (0.39) SLC1A2SLC1A1GABRR1MEN1BLM
SCHEMBL20979921 0.93 HSD11B1 (0.39) SLC1A2SLC1A1GABRR1MEN1BLM
SCHEMBL19733793 0.93 HSD11B1 (0.39) SLC1A2SLC1A1GABRR1MEN1BLM
SCHEMBL20979912 0.93 HSD11B1 (0.39) SLC1A2SLC1A1GABRR1MEN1BLM
SCHEMBL20226843 0.93 HSD11B1 (0.39) SLC1A2SLC1A1GABRR1MEN1BLM
SCHEMBL11695757 0.93 PEPD (0.43) GABRR1PEPDMEN1BLMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9115169-B2 Method of treating tumors LYTIX BIOPHARMA AS (NO) 2015-08-25 US disclosed
US-9109048-B2 Inhibition of tumor growth LYTIX BIOPHARMA AS (NO) 2015-08-18 US disclosed
US-20140147794-A1 METHOD OF FORMING PHOTORESIST PATTERN JSR CORPORATION (JP) 2014-05-29 US disclosed
US-20140037657-A1 INHIBITION OF TUMOR GROWTH LYTIX BIOPHARMA AS (NO) 2014-02-06 US disclosed
US-8535872-B2 Thermally cured underlayer for lithographic application FUJIFILM ELECTRONIC MATERIALS, U.S.A., INC. (US) 2013-09-17 US disclosed
US-8435718-B2 Upper layer-forming composition and photoresist patterning method JSR CORPORATION (JP) 2013-05-07 US disclosed
US-8283315-B2 Inhibition of tumour growth LYTIX BIOPHARMA AS (NO) 2012-10-09 US disclosed
US-20120178871-A1 THERMALLY CURED UNDERLAYER FOR LITHOGRAPHIC APPLICATION DE BINOD B (US) 2012-07-12 US disclosed
US-20120171613-A1 UPPER LAYER FILM-FORMING COMPOSITION AND METHOD OF FORMING PHOTORESIST PATTERN JSR CORPORATION (JP) 2012-07-05 US disclosed
US-20120108520-A1 Antimicrobial Compounds and Formulations LYTIX BIOPHARMA AS (NO) 2012-05-03 US disclosed
US-6238842-B1 SUITABLE FOR USE WITH AN EXPOSURE LIGHT HAVING A WAVELENGTH OF 250 NM OR SHORTER, ESPECIALLY 220 NM OR SHORTER; ACID GENERATING COMPOUND; RESIN HAVING MONOVALENT POLYALICYCLIC GROUPS FUJI PHOTO FILM CO., LTD. (JP) 2001-05-29 US disclosed
US-6187504-B1 PHOTOSENSITIVE BLEND CONTAINING A NAPHTHALENE SULFONIUM SULFONATE DERIVATIVE PHOTOACID GENERATOR, RESIN HAVING ALKALI INSOLUBLE GROUPS CLEAVABLE BY ACID, AN ALKALI SOLUBLE RESIN AND A SOLUBILITY CONTROL AGENT; POSITIVES, RESOLUTION JSR CORPORATION (JP) 2001-02-13 US disclosed
EP-0564924-B1 2-Oxoethyl derivatives as immunosuppressants BAYER AG (US) 1998-09-09 EP disclosed
EP-0849634-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-06-24 EP disclosed
EP-0564924-A2 2-Oxoethyl derivatives as immunosuppressants Bayer Corporation (US) 1993-10-13 EP disclosed
EP-0421752-A2 Substituted acrylamido-penicillanic acid derivatives Beecham Group p.l.c. (GB) 1991-04-10 EP disclosed
US-4925956-A Novel process for manufacturing optically active carbacyclin intermediates SCHERING AKTIENGESELLSCHAFT (DE) 1990-05-15 US disclosed
US-4925956-A Novel process for manufacturing optically active carbacyclin intermediates SCHERING AKTIENGESELLSCHAFT (DE) 1990-05-15 US disclosed
US-4102994-A Aliphatic amido-quaternary ammonium anti-microbial compounds COLGATE-PALMOLIVE COMPANY (US) 1978-07-25 US disclosed
US-4046873-A Alicyclic amido-quaternary ammonium anti-bacterial agents COLGATE PALMOLIVE COMPANY (US) 1977-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108520-A1 Antimicrobial Compounds and Formulations VIP, NONO, CLPTM1 SLC1A2 2948/4885SLC1A1 2298/4885GABRR1 3167/4885
US-20140037657-A1 INHIBITION OF TUMOR GROWTH STING1, VIP, MIF SLC1A2 1765/4885SLC1A1 1141/4885GABRR1 2567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.