Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | PGK1 | P00558 | 1/20 | 0.52 |
| ▸ | PGK2 | P07205 | 1/20 | 0.52 |
| ▸ | NT5E | P21589 | 6/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034054 | 0.93 | ADORA3 (0.59) | ADORA3TP53SLC29A1TDP1PGK1 | |
| SCHEMBL5035415 | 0.93 | ADORA3 (0.59) | ADORA3TP53SLC29A1TDP1PGK1 | |
| SCHEMBL5034068 | 0.85 | ADORA3 (0.59) | ADORA3TP53SLC29A1ADORA1ADORA2A | |
| SCHEMBL5034070 | 0.84 | ADORA3 (0.58) | ADORA3TDP1ADORA1ADORA2AADORA2B | |
| SCHEMBL465954 | 0.84 | ADORA2A (0.56) | ADORA3NT5EADORA1ADORA2AADORA2B | |
| Water SCHEMBL3630434 | 0.83 | ADORA2A (0.55) | ADORA3NT5EADORA1ADORA2AADORA2B | |
| SCHEMBL5038188 | 0.83 | ADORA3 (0.59) | ADORA3TP53SLC29A1TDP1PGK1 | |
| SCHEMBL5034544 | 0.82 | ADORA1 (0.61) | ADORA3SLC29A1NT5EADORA1ADORA2A | |
| SCHEMBL5397146 | 0.82 | ADORA3 (0.58) | ADORA3TP53SLC29A1TDP1PGK1 | |
| SCHEMBL5032145 | 0.81 | ADORA3 (0.58) | ADORA3TP53SLC29A1TDP1PGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881991-A1 | A1 ADENOSINE RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2008-01-30 | — | — | EP | disclosed |
| WO-2006125211-A1 | A1 ADENOSINE RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2006-11-23 | — | — | WO | disclosed |