Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | PGK1 | P00558 | 3/20 | 0.53 |
| ▸ | PGK2 | P07205 | 3/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.52 |
| ▸ | NT5E | P21589 | 3/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034055 | 0.83 | ADORA1 (0.60) | ADORA3SLC29A1ADORA2AADORA1NT5E | |
| SCHEMBL5038188 | 0.82 | ADORA3 (0.59) | ADORA3TP53SLC29A1TDP1PGK1 | |
| SCHEMBL6582374 | 0.81 | ADORA3 (0.63) | ADORA3TP53SLC29A1TDP1PGK1 | |
| SCHEMBL6584541 | 0.81 | ADORA3 (0.64) | ADORA3TP53SLC29A1TDP1PGK1 | |
| SCHEMBL5034054 | 0.81 | ADORA3 (0.59) | ADORA3TP53SLC29A1TDP1PGK1 | |
| SCHEMBL5040344 | 0.81 | ADORA3 (0.59) | ADORA3TP53SLC29A1TDP1PGK1 | |
| SCHEMBL5035415 | 0.81 | ADORA3 (0.59) | ADORA3TP53SLC29A1TDP1PGK1 | |
| SCHEMBL5397146 | 0.80 | ADORA3 (0.58) | ADORA3TP53SLC29A1TDP1PGK1 | |
| SCHEMBL4136495 | 0.79 | ADORA3 (0.61) | ADORA3TP53SLC29A1TDP1ADORA2A | |
| SCHEMBL4136498 | 0.79 | ADORA3 (0.61) | ADORA3TP53SLC29A1TDP1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881991-A1 | A1 ADENOSINE RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2008-01-30 | — | — | EP | claimed |
| WO-2006125211-A1 | A1 ADENOSINE RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2006-11-23 | — | — | WO | claimed |
| EP-1881991-A1 | A1 ADENOSINE RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2008-01-30 | — | — | EP | disclosed |
| WO-2006125211-A1 | A1 ADENOSINE RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2006-11-23 | — | — | WO | disclosed |