SCHEMBL504039

SCHEMBL504039

C=CCN(CC=C)CC(=C)C(=C)CN(CC=C)CC=C

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 2/20 0.32
TSHR P16473 3/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
OPRM1 P35372 1/20 0.31
OPRD1 P41143 1/20 0.31
OPRK1 P41145 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL327211 0.83 ALOX15 (0.45) MEN1KMT2AALDH1A1
SCHEMBL2058525 0.81
SCHEMBL821810 0.81 MEN1 (0.37) MEN1KMT2AALDH1A1TSHR
SCHEMBL9604430 0.80 MEN1 (0.32) MEN1KMT2AALDH1A1
SCHEMBL2820192 0.78 CYP1A2 (0.46) MEN1KMT2AALDH1A1TSHRCYP1A2
SCHEMBL609861 0.78 MEN1 (0.31) MEN1KMT2AALDH1A1TSHR
Hydrochloric Acid SCHEMBL11444043 0.78 OPRM1 (0.32) MEN1KMT2AALDH1A1OPRM1OPRD1
SCHEMBL2058236 0.75
SCHEMBL10337792 0.75 CYP3A4 (0.34) MEN1KMT2AALDH1A1TSHRCYP3A4
SCHEMBL175511 0.75 SMN1; SMN2 (0.38) MEN1KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020151673-A1 Functionalized diene monomers and polymers containing functionalized dienes and methods for their preparation SHEARES VALERIE V (US) 2002-10-17 US claimed
US-11912798-B2 Rubber with backbone and end-group functionalization THE GOODYEAR TIRE & RUBBER COMPANY (US) 2024-02-27 US disclosed
US-20220177610-A1 RUBBER WITH BACKBONE AND END-GROUP FUNCTIONALIZATION MIZUHO BANK, LTD., AS ADMINISTRATIVE AGENT 2022-06-09 US disclosed
US-20220169752-A1 METHOD OF MAKING A SILICA/CELLULOSE HYBRID THE GOODYEAR TIRE & RUBBER COMPANY 2022-06-02 US disclosed
US-9587060-B2 Functionalized rubbery polymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 2017-03-07 US disclosed
US-9550839-B2 Copolymers of conjugated triene monomers for improved filler interaction THE GOODYEAR TIRE & RUBBER COMPANY (US) 2017-01-24 US disclosed
US-20150376343-A1 COPOLYMERS OF CONJUGATED TRIENE MONOMERS FOR IMPROVED FILLER INTERACTION THE GOODYEAR TIRE & RUBBER COMPANY (US) 2015-12-31 US disclosed
US-9079980-B2 Copolymers of conjugated triene monomers for improved filler interaction THE GOODYEAR TIRE & RUBBER COMPANY (US) 2015-07-14 US disclosed
US-8299290-B2 Boron containing functionalizing agent THE GOODYEAR TIRE & RUBBER COMPANY (US) 2012-10-30 US disclosed
US-20120048446-A1 COPOLYMERS OF CONJUGATED TRIENE MONOMERS FOR IMPROVED FILLER INTERACTION THE GOODYEAR TIRE & RUBBER COMPANY (US) 2012-03-01 US disclosed
US-6630552-B1 Butadiene-styrene copolymers with heterocyclic amine compounds THE GOODYEAR TIRE & RUBBER COMPANY 2003-10-07 US disclosed
US-6627722-B2 Rubber comprising comonomers of conjugated diolefin and vinyllaromatic compound substituted with N-heterocycle; tire treads GOODYEAR TIRE & RUBBER COMPANY, THE 2003-09-30 US disclosed
US-6627721-B1 Rubbery polymer comprised of comonomers of conjugated diene and styrene substited with N-heterocycle or sulfide; hoses, power transmission belts THE GOODYEAR TIRE & RUBBER COMPANY 2003-09-30 US disclosed
US-20030134997-A1 Functionalized elastomers THE GOODYEAR TIRE & RUBBER COMPANY 2003-07-17 US disclosed
US-6583260-B2 Such as 2-(N,N-dimethylaminomethyl)-1,3- butadiene); for use in adhesives, sealants, surfactants, elastomers, ionomers, coatings and membranes IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2003-06-24 US disclosed
US-6583260-B2 Such as 2-(N,N-dimethylaminomethyl)-1,3- butadiene); for use in adhesives, sealants, surfactants, elastomers, ionomers, coatings and membranes IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2003-06-24 US disclosed
US-20020151673-A1 Functionalized diene monomers and polymers containing functionalized dienes and methods for their preparation SHEARES VALERIE V (US) 2002-10-17 US disclosed
US-20020151673-A1 Functionalized diene monomers and polymers containing functionalized dienes and methods for their preparation SHEARES VALERIE V (US) 2002-10-17 US disclosed
US-6344538-B1 REACTION OF 3-BROMOMETHYL-2,5-HYDROTHIOPHENE-1,1-DIOXIDE WITH NUCLEOPHILE WITH AMINE, HYDROXY, CARBOXY ACID, ESTER OR NITRILE IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2002-02-05 US disclosed
US-6344538-B1 REACTION OF 3-BROMOMETHYL-2,5-HYDROTHIOPHENE-1,1-DIOXIDE WITH NUCLEOPHILE WITH AMINE, HYDROXY, CARBOXY ACID, ESTER OR NITRILE IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2002-02-05 US disclosed