Benzimidazole

Benzimidazole

SCHEMBL5040740

CO.c1ccc2[nH]cnc2c1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.47
ALDH1A1 P00352 4/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
HPGD P15428 3/20 0.47
RAB9A P51151 2/20 0.47
HTT P42858 1/20 0.47
QPCT Q16769 1/20 0.47
QPCTL Q9NXS2 1/20 0.47
MMP12 P39900 1/20 0.46
PARP1 P09874 2/20 0.45
PDPK1 O15530 1/20 0.45
CA12 O43570 1/20 0.45
ALOX15 P16050 1/20 0.45
CA9 Q16790 1/20 0.45
TNKS2 Q9H2K2 1/20 0.45
PRKCI P41743 1/20 0.45
MAPT P10636 2/20 0.44
RAD52 P43351 1/20 0.44
CTNNB1 P35222 1/20 0.44
WNT3A P56704 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzimidazole SCHEMBL28307504 0.95 SMN1; SMN2 (0.48) KDM4EALDH1A1SMN1; SMN2HPGDRAB9A
Benzimidazole SCHEMBL29218507 0.93 MMP12 (0.47) KDM4EALDH1A1SMN1; SMN2HPGDRAB9A
Benzimidazole SCHEMBL29358377 0.93
Benzimidazole SCHEMBL6009 0.93
Benzimidazole SCHEMBL461969 0.93 SMN1; SMN2 (0.50) KDM4EALDH1A1SMN1; SMN2HPGDRAB9A
Benzimidazole SCHEMBL29408372 0.93
Benzimidazole SCHEMBL10931770 0.93 SMN1; SMN2 (0.50) KDM4EALDH1A1SMN1; SMN2HPGDRAB9A
Benzimidazole SCHEMBL28381628 0.91 MMP12 (0.46) KDM4EALDH1A1SMN1; SMN2HPGDRAB9A
Benzimidazole SCHEMBL2334176 0.91 PRKCI (0.50) KDM4EALDH1A1SMN1; SMN2HPGDRAB9A
Benzimidazole SCHEMBL376958 0.91 MMP12 (0.46) KDM4EALDH1A1SMN1; SMN2HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116130683-B Ternary nano nitride material for solid metal fuel cell and preparation method thereof 郑州佛光发电设备股份有限公司 2024-03-08 CN claimed
CN-114452956-B Environment-friendly functional copper mesh material and preparation method and application thereof 辽宁大学 2023-12-08 CN claimed
CN-116130683-A Ternary nano nitride material for solid metal fuel cell and preparation method thereof 郑州大学 2023-05-16 CN claimed
CN-114452956-A Environment-friendly functionalized copper mesh material and preparation method and application thereof 辽宁大学 2022-05-10 CN claimed
CN-113096965-A Multi-level structure nickel-cobalt bimetal layered hydroxide material and preparation method thereof 郑州大学 2021-07-09 CN claimed
CN-117943018-A Method for preparing integrated blocky monoatomic catalyst by one-step molding and application 中钢集团鞍山热能研究院有限公司 2024-04-30 CN disclosed
CN-116130683-B Ternary nano nitride material for solid metal fuel cell and preparation method thereof 郑州佛光发电设备股份有限公司 2024-03-08 CN disclosed
CN-114452956-B Environment-friendly functional copper mesh material and preparation method and application thereof 辽宁大学 2023-12-08 CN disclosed
CN-116130683-A Ternary nano nitride material for solid metal fuel cell and preparation method thereof 郑州大学 2023-05-16 CN disclosed
CN-113096965-B Multi-level structure nickel-cobalt bimetal layered hydroxide material and preparation method thereof 郑州大学 2022-12-27 CN disclosed
CN-113096965-B Multi-level structure nickel-cobalt bimetal layered hydroxide material and preparation method thereof 郑州大学 2022-12-27 CN disclosed
CN-115282963-A Monatomic catalyst taking biomass as precursor, preparation method and application thereof 西北工业大学 2022-11-04 CN disclosed
EP-1001767-A1 ANTI-VIRAL COMPOUNDS ELI LILLY AND COMPANY (US) 2000-05-24 EP disclosed
WO-1998055120-A1 ANTI-VIRAL COMPOUNDS ELI LILLY AND COMPANY (US) 1998-12-10 WO disclosed
US-4492708-A Antiviral benzimidazoles ELI LILLY AND COMPANY (US) 1985-01-08 US disclosed
EP-0111993-A2 Improvements in or relating to benzimidazoles ELI LILLY AND COMPANY (US) 1984-06-27 EP disclosed
US-4424362-A Process for preparing a trans-6-propenyl benzimidazole ELI LILLY AND COMPANY (US) 1984-01-03 US disclosed
US-4424362-A Process for preparing a trans-6-propenyl benzimidazole ELI LILLY AND COMPANY (US) 1984-01-03 US disclosed
US-4420479-A 1-SUBSTITUTED, 2-AMINO-BENZIMIDAZOLES ELI LILLY AND COMPANY (US) 1983-12-13 US disclosed
EP-0091795-A1 Olefinic benzimidazoles ELI LILLY AND COMPANY (US) 1983-10-19 EP disclosed