SCHEMBL504078

SCHEMBL504078

C1=C\c2ccccc2-c2ccccc2\C=C/1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.46
KMT2A Q03164 6/20 0.46
LMNA P02545 5/20 0.46
MAPT P10636 4/20 0.46
ALDH1A1 P00352 4/20 0.46
ALOX15 P16050 3/20 0.46
IDO1 P14902 2/20 0.46
HSD17B10 Q99714 2/20 0.46
KDM4E B2RXH2 2/20 0.46
BCHE P06276 2/20 0.46
POLB P06746 2/20 0.46
PTPRC P08575 2/20 0.46
THRB P10828 2/20 0.46
CES1 P23141 2/20 0.46
RECQL P46063 2/20 0.46
PKM P14618 1/20 0.46
HPGD P15428 1/20 0.46
PTPN1 P18031 1/20 0.46
ACHE P22303 1/20 0.46
PTPN22 Q9Y2R2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL568780 1.00 MEN1 (0.46) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL9985286 0.97 MEN1 (0.44) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL9985289 0.97 MEN1 (0.44) MEN1KMT2ALMNAMAPTALDH1A1
Biphenyl SCHEMBL27667990 0.89 ALDH1A1 (0.47) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL15226315 0.84 ALDH1A1 (0.37) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL3769766 0.83 MEN1 (0.55) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL11049520 0.79 CDC25B (0.52) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL11049499 0.79 CDC25B (0.52) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL11049537 0.79 CDC25B (0.52) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL1478315 0.79 MAPT (0.38) MEN1KMT2ALMNAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7708 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747409-A2 COLLECTION, ASSESSMENT AND EARLY DETECTION OF HUMAN LUNG CANCER BIOMARKERS IN EXHALED BREATH CONDENSATES OF MOUSE ANIMAL MODELS Hackensack Meridian Health, Inc. (US) 2026-05-27 EP claimed
CN-122071742-A High-sensitivity tumor mutation detection method based on co-primer co-F 张家港市第一人民医院 2026-05-22 CN claimed
CN-122071705-A Lactose modified nucleic acid, preparation method thereof and application thereof in CRISPR-Cas9 inhibition 南京师范大学 2026-05-22 CN claimed
CN-122063266-A Preparation method and application of novel azobenzene modified nanopore probe 绵阳师范学院 2026-05-19 CN claimed
WO-2026102134-A1 ANALYTE BINDING COMPOSITIONS, METHODS, AND SYSTEMS FREENOME HOLDINGS, INC. (US) 2026-05-15 WO claimed
US-20260132456-A1 Methods for Extraction and Sequencing of Nucleic Acid EARLHAM ENTPR LTD (GB) 2026-05-14 US claimed
EP-4739804-A1 METHODS AND COMPOSITIONS FOR CHARACTERIZING VIRAL PARTICLES IN A BIOLOGICAL SAMPLE NanoMosaic Inc. (US) 2026-05-13 EP claimed
US-12624375-B2 Methods for co-activating in vitro non-standard amino acid (nsAA) incorporation and glycosylation in crude cell lysates NORTHWESTERN UNIVERSITY (US) 2026-05-12 US claimed
CN-122010900-A Organic ionic liquid formed by mixing double medicaments and application thereof 苏州大学 2026-05-12 CN claimed
CN-122005857-A Double-antibody modified vesicle STING agonist, preparation method and application 苏州大学 2026-05-12 CN claimed
WO-2012166653-A2 METHODS FOR COUPLING TARGETING PEPTIDES ONTO RECOMBINANT LYSOSOMAL ENZYMES FOR IMPROVED TREATMENTS OF LYSOSOMAL STORAGE DISEASES CALLIDUS BIOPHARMA, INC. (US) 2012-12-06 WO claimed
US-8258347-B2 Cyclopropenones and the photochemical generation of cyclic alkynes therefrom UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2012-09-04 US claimed
US-20120208722-A1 SURFACE ENHANCED RAMAN SPECTROSCOPY PLATFORMS AND METHODS NATIONAL INSTITUTES OF HEALTH 2012-08-16 US claimed
US-20120172575-A1 ALKYNES AND METHODS OF REACTING ALKYNES WITH 1,3-DIPOLE-FUNCTIONAL COMPOUNDS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2012-07-05 US claimed
WO-2012047663-A2 METHODS INCLUDING LATENT 1,3-DIPOLE-FUNCTIONAL COMPOUNDS AND MATERIALS PREPARED THEREBY UNIVERSITY OF GEORGIA REASERCH FOUNDATION, INC. (US) 2012-04-12 WO claimed
US-20120053299-A1 Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2012-03-01 US claimed
WO-2012006556-A2 DETECTION OF ANALYTES Life Technologies Corporation (US) 2012-01-12 WO claimed
EP-2334630-A2 CARBONYL DERIVATIVES HAVING A C3 SYMMETRY, THEIR PREPARATION AND USES THEREOF Universita'Degli Studi di Roma "La Sapienza" (IT) 2011-06-22 EP claimed
US-20100210854-A1 Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2010-08-19 US claimed
WO-2010038252-A2 CARBONYL DERIVATIVES HAVING A C3 SYMMETRY, THEIR PREPARATION AND USES THEREOF UNIVERSITÀ DEGLI STUDI DI ROMA LA SAPIENZA (IT) 2010-04-08 WO claimed