SCHEMBL9985286

SCHEMBL9985286

C1=C\C=C/c2ccccc2-c2ccccc2/C=C\C=C/1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.44
KMT2A Q03164 6/20 0.44
LMNA P02545 5/20 0.44
MAPT P10636 4/20 0.44
ALDH1A1 P00352 4/20 0.44
ALOX15 P16050 3/20 0.44
IDO1 P14902 2/20 0.44
HSD17B10 Q99714 2/20 0.44
KDM4E B2RXH2 2/20 0.44
BCHE P06276 2/20 0.44
POLB P06746 2/20 0.44
PTPRC P08575 2/20 0.44
THRB P10828 2/20 0.44
CES1 P23141 2/20 0.44
RECQL P46063 2/20 0.44
PKM P14618 1/20 0.44
HPGD P15428 1/20 0.44
PTPN1 P18031 1/20 0.44
ACHE P22303 1/20 0.44
PTPN22 Q9Y2R2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9985289 1.00 MEN1 (0.44) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL568780 0.97 MEN1 (0.46) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL504078 0.97 MEN1 (0.46) MEN1KMT2ALMNAMAPTALDH1A1
Biphenyl SCHEMBL27667990 0.86 ALDH1A1 (0.47) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL1098771 0.83 MAPT (0.38) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL1478315 0.83 MAPT (0.38) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL11049499 0.82 CDC25B (0.52) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL11049520 0.82 CDC25B (0.52) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL11049537 0.82 CDC25B (0.52) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL15226315 0.82 ALDH1A1 (0.37) MEN1KMT2ALMNAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9099660-B2 Alkynyl-substituted indenofluorenes useful in electronic and electro-optical devices UNIVERSITY OF OREGON (US) 2015-08-04 US disclosed
US-20130096336-A1 ALKYNYL-SUBSTITUTED INDENOFLUORENES USEFUL IN ELECTRONIC AND ELECTRO-OPTICAL DEVICES UNIVERSITY OF OREGON 2013-04-18 US disclosed
WO-2011159763-A1 ALKYNYL-SUBSTITUTED INDENOFLUORENES USEFUL IN ELECTRONIC AND ELECTRO-OPTICAL DEVICES STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OFOREGON (US) 2011-12-22 WO disclosed