SCHEMBL5040807

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5034268	0.90	NR3C1 (0.45)	PGRARNR3C2NR3C1
	SCHEMBL2393893	0.88	PGR (0.49)	PGRARNR3C2NR3C1ESR1
	SCHEMBL5032342	0.86	PGR (0.46)	PGRARNR3C2NR3C1
	SCHEMBL5040872	0.84	PGR (0.51)	PGRARNR3C2NR3C1
	SCHEMBL5034865	0.83	PGR (0.51)	PGRARNR3C2NR3C1ESR1
	SCHEMBL2393963	0.81	PGR (0.39)	PGRARNR3C2NR3C1
	SCHEMBL2390510	0.78	NR3C1 (0.50)	PGRARNR3C2NR3C1
	SCHEMBL5034967	0.78	PGR (0.45)	PGRARNR3C2NR3C1ESR1
	SCHEMBL2393555	0.78	PGR (0.50)	PGRARNR3C2NR3C1ESR1
	SCHEMBL5034828	0.77	PGR (0.49)	PGRARNR3C2NR3C1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.