Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 20/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 20/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6190309 | 0.85 | SLC6A2 (0.31) | SLC6A2SLC6A4SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL1920550 | 0.73 | NPC1 (0.41) | SLC6A2SLC6A4 | |
| Trifluoroacetic Acid SCHEMBL5443966 | 0.72 | GABRP (0.39) | SLC6A2SLC6A4SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL7446778 | 0.72 | GABRP (0.39) | SLC6A2SLC6A4SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL5443972 | 0.72 | GABRP (0.39) | SLC6A2SLC6A4SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL3006963 | 0.68 | GABRP (0.35) | SLC6A2SLC6A4SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL8435138 | 0.67 | SLC6A4 (0.42) | SLC6A2SLC6A4SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL8520995 | 0.67 | SLC6A4 (0.42) | SLC6A2SLC6A4SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL26599567 | 0.66 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5040950 | 0.66 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622914-A4 | NEW PIPERIDINYLAMINO-THIENO 2,3-D PYRIMIDINE COMPOUNDS | EPIX DELAWARE INC (US) | 2008-03-12 | — | — | EP | disclosed |
| EP-1622914-A2 | NEW PIPERIDINYLAMINO-THIENO 2,3-D PYRIMIDINE COMPOUNDS | Predix Pharmaceuticals Holdings, Inc. (US) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004089312-A2 | NEW PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | PREDIX PHARMACEUTICALS HOLDINGS, INC. (US) | 2004-10-21 | — | — | WO | disclosed |