Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.55 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 14/20 | 0.51 |
| ▸ | MASP2 | O00187 | 3/20 | 0.51 |
| ▸ | F10 | P00742 | 3/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.50 |
| ▸ | F7 | P08709 | 2/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5041503 | 1.00 | TPSAB1 (0.55) | TPSAB1ST14F2MASP2F10 | |
| Hydrochloric Acid SCHEMBL5037455 | 0.99 | TPSAB1 (0.54) | TPSAB1ST14F2MASP2F10 | |
| Hydrochloric Acid SCHEMBL5037453 | 0.99 | TPSAB1 (0.54) | TPSAB1ST14F2MASP2F10 | |
| SCHEMBL5047919 | 0.88 | TPSAB1 (0.57) | TPSAB1ST14F2MASP2F10 | |
| SCHEMBL5047928 | 0.88 | TPSAB1 (0.57) | TPSAB1ST14F2MASP2F10 | |
| Hydrochloric Acid SCHEMBL5037758 | 0.87 | TPSAB1 (0.56) | TPSAB1ST14F2MASP2F10 | |
| Hydrochloric Acid SCHEMBL5037760 | 0.87 | TPSAB1 (0.56) | TPSAB1ST14F2MASP2F10 | |
| SCHEMBL5041565 | 0.80 | TPSAB1 (0.62) | TPSAB1ST14F2MASP2F10 | |
| SCHEMBL5041567 | 0.80 | TPSAB1 (0.62) | TPSAB1ST14F2MASP2F10 | |
| SCHEMBL5037516 | 0.80 | SLC1A3 (0.51) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567498-B1 | MANDELIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-01-23 | — | — | EP | disclosed |
| EP-1567498-A2 | MANDELIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048335-A2 | MANDELIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-06-10 | — | — | WO | disclosed |