Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1222603 | 0.85 | ALDH1A1 (0.72) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL16703334 | 0.84 | PTPN11 (0.59) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL4283912 | 0.84 | HCAR2 (0.55) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL27821864 | 0.84 | NPC1 (0.53) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL1193921 | 0.84 | SMN1; SMN2 (0.71) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL3593476 | 0.82 | CDC7 (0.63) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL14156945 | 0.81 | KDM4E (0.55) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL23794761 | 0.80 | HSD17B1 (0.62) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL1986146 | 0.80 | HDAC1 (0.57) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL31341283 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306125-A1 | Compounds and Methods for Modulating Fx-Receptors | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR COLLATERAL AGENT | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306125-A1 | Compounds and Methods for Modulating Fx-Receptors | F2R, TBXA2R, PTAFR | SMN1; SMN2 4396/4885NPC1 426/4885RAB9A 2636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.