Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CD81 | P60033 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1286052 | 0.98 | PAOX (0.47) | PAOXRAB9ATBXAS1ALDH1A1KDM4E | |
| SCHEMBL1285641 | 0.98 | PAOX (0.47) | PAOXRAB9ATBXAS1ALDH1A1KDM4E | |
| SCHEMBL1285651 | 0.94 | PAOX (0.42) | PAOXRAB9ATBXAS1ALDH1A1KDM4E | |
| SCHEMBL504158 | 0.86 | CD81 (0.39) | PAOXRAB9AALDH1A1CD81CYP1A2 | |
| SCHEMBL5682570 | 0.86 | CD81 (0.39) | PAOXRAB9AALDH1A1CD81CYP1A2 | |
| SCHEMBL1317424 | 0.82 | EP300 (0.48) | TBXAS1CD81EP300 | |
| SCHEMBL1317422 | 0.82 | EP300 (0.48) | TBXAS1CD81EP300 | |
| SCHEMBL4845826 | 0.81 | MEN1 (0.39) | RAB9AALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1325679 | 0.80 | EP300 (0.52) | TBXAS1CD81CYP1A2EP300 | |
| SCHEMBL4131095 | 0.80 | EP300 (0.52) | TBXAS1CD81CYP1A2EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976362-B1 | METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2023-06-07 | — | — | EP | claimed |
| US-20120088861-A1 | WATER-PROCESSABLE SILICONE-CONTAINING PREPOLYMERS AND USES THEREOF | ALCON INC. (CH) | 2012-04-12 | — | — | US | claimed |
| US-9684095-B2 | Hydrophilized carbosiloxane vinylic monomers | NOVARTIS AG (CH) | 2017-06-20 | — | — | US | disclosed |
| US-9637582-B2 | Polymerizable polysiloxanes with hydrophilic substituents | NOVARTIS AG (CH) | 2017-05-02 | — | — | US | disclosed |
| US-9500775-B2 | Actinically-crosslinkable amphiphilic prepolymers | NOVARTIS AG (CH) | 2016-11-22 | — | — | US | disclosed |
| US-20160090432-A1 | POLYMERIZABLE POLYSILOXANES WITH HYDROPHILIC SUBSTITUENTS | ALCON INC. (CH) | 2016-03-31 | — | — | US | disclosed |
| US-20150369962-A1 | ACTINICALLY-CROSSLINKABLE AMPHIPHILIC PREPOLYMERS | ALCON INC. (CH) | 2015-12-24 | — | — | US | disclosed |
| US-9187601-B2 | Water-processable silicone-containing prepolymers and uses thereof | NOVARTIS AG (CH) | 2015-11-17 | — | — | US | disclosed |
| US-20150309210-A1 | HYDROPHILIZED CARBOSILOXANE VINYLIC MONOMERS | ALCON INC. (CH) | 2015-10-29 | — | — | US | disclosed |
| US-9103965-B2 | Amphiphilic siloxane-containing vinylic monomers and uses thereof | NOVARTIS AG (CH) | 2015-08-11 | — | — | US | disclosed |
| US-9005700-B2 | Method for making UV-absorbing ophthalmic lenses | NOVARTIS AG (CH) | 2015-04-14 | — | — | US | disclosed |
| US-20130095235-A1 | METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES | NOVARTIS AG (CH) | 2013-04-18 | — | — | US | disclosed |
| US-20120088861-A1 | WATER-PROCESSABLE SILICONE-CONTAINING PREPOLYMERS AND USES THEREOF | ALCON INC. (CH) | 2012-04-12 | — | — | US | disclosed |
| US-20110063567-A1 | PREPOLYMERS SUITABLE FOR MAKING ULTRA-VIOLET ABSORBING CONTACT LENSES | ALCON INC. (CH) | 2011-03-17 | — | — | US | disclosed |
| US-7384984-B2 | Reactive hydrophilic oligomers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-06-10 | — | — | US | disclosed |
| US-7074858-B2 | Reactive oligomers | HEILMANN STEVEN M | 2006-07-11 | — | — | US | disclosed |
| US-7015286-B2 | Reactive oligomers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-03-21 | — | — | US | disclosed |
| US-20050131148-A1 | Reactive hydrophilic oligomers | 3M INNOVATIVE PROPERTIES COMPANY | 2005-06-16 | — | — | US | disclosed |
| US-20040059044-A1 | Oligomeric dyes and use thereof | 3M INNOVATIVE PROPERTIES COMPANY | 2004-03-25 | — | — | US | disclosed |
| US-20030212210-A1 | Reactive oligomers | 3M INNOVATIVE PROPERTIES COMPANY | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150309210-A1 | HYDROPHILIZED CARBOSILOXANE VINYLIC MONOMERS | VCL, MACF1, HCAR1 | PAOX 295/4885RAB9A 4461/4885TBXAS1 1697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.