Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.32 |
| ▸ | FABP1 | P07148 | 3/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19900445 | 0.90 | POLB (0.40) | NPC1RAB9APOLBALDH1A1L3MBTL1 | |
| SCHEMBL1326560 | 0.73 | ALDH1A1 (0.44) | POLBALDH1A1L3MBTL1TSHR | |
| SCHEMBL1179711 | 0.69 | NR1H4 (0.38) | NR1H4POLBALDH1A1L3MBTL1TSHR | |
| SCHEMBL19900076 | 0.67 | STAT1 (0.50) | NPC1RAB9ASTAT3STAT1POLB | |
| SCHEMBL3639201 | 0.67 | ALDH1A1 (0.36) | NPC1RAB9ANR1H4POLBALDH1A1 | |
| SCHEMBL10405275 | 0.66 | KMT2A (0.40) | NPC1RAB9APOLBALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL30437434 | 0.66 | STAT1 (0.49) | NPC1RAB9ASTAT3STAT1POLB | |
| Iodide SCHEMBL29388459 | 0.66 | STAT1 (0.49) | NPC1RAB9ASTAT3STAT1POLB | |
| SCHEMBL20043329 | 0.64 | NR1H4 (0.48) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL20944650 | 0.64 | NR1H4 (0.46) | NR1H4FABP1ALDH1A1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106946867-B | FXR receptor modulators and its preparation method and application | 广州市恒诺康医药科技有限公司 | 2019-11-12 | — | — | CN | disclosed |
| US-20080306125-A1 | Compounds and Methods for Modulating Fx-Receptors | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR COLLATERAL AGENT | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306125-A1 | Compounds and Methods for Modulating Fx-Receptors | F2R, TBXA2R, PTAFR | NPC1 426/4885RAB9A 2636/4885STAT3 3224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.