Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 4/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3787087 | 0.88 | MAP4K4 (0.54) | MAP4K4MAOAMEN1PSIP1AXL | |
| SCHEMBL30013886 | 0.87 | — | — | |
| SCHEMBL1488513 | 0.87 | — | — | |
| SCHEMBL3790176 | 0.86 | MAOA (0.59) | MAP4K4MAOAMEN1PSIP1AXL | |
| SCHEMBL3788673 | 0.86 | TAAR1 (0.52) | MAP4K4MAOAMAPTTDP1ALDH1A1 | |
| SCHEMBL13068990 | 0.84 | MAOA (0.52) | MAP4K4MAOAMEN1PSIP1AXL | |
| SCHEMBL28488286 | 0.82 | TSHR (0.48) | MEN1MAPTKMT2ACYP3A4CYP17A1 | |
| SCHEMBL30288275 | 0.80 | TSHR (0.59) | MAOAMEN1KDM4EKMT2AALDH1A1 | |
| SCHEMBL1038467 | 0.80 | TSHR (0.59) | MAOAMEN1KDM4EKMT2AALDH1A1 | |
| SCHEMBL3786635 | 0.80 | MAP4K4 (0.46) | MAP4K4MAOAMEN1PSIP1AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020071478-A1 | NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL CONTAINING SAME | 出光興産株式会社 | 2020-04-09 | — | — | WO | disclosed |
| EP-1485093-B1 | DI-ARYL SUBSTITUTED TETRAZOLE MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR-5 | MERCK SHARP & DOHME (US) | 2010-11-03 | — | — | EP | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |