Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4427341 | 0.85 | SLC6A9 (0.72) | SLC6A9KCNH2 | |
| SCHEMBL3756964 | 0.73 | NPSR1 (0.47) | LMNASMN1; SMN2TSHRNPSR1RAB9A | |
| SCHEMBL3756961 | 0.73 | NPSR1 (0.47) | LMNASMN1; SMN2TSHRNPSR1RAB9A | |
| SCHEMBL5047851 | 0.72 | SLC6A9 (0.76) | SLC6A9KCNH2 | |
| SCHEMBL5043261 | 0.71 | SLC6A9 (0.76) | SLC6A9KCNH2 | |
| SCHEMBL5041853 | 0.71 | SLC6A9 (0.73) | SLC6A9KCNH2 | |
| SCHEMBL2636948 | 0.70 | NOTUM (0.60) | LMNACHRM4MAPTGAAHTT | |
| SCHEMBL5042701 | 0.69 | SLC6A9 (0.79) | SLC6A9KCNH2 | |
| SCHEMBL4433347 | 0.69 | SLC6A9 (0.71) | SLC6A9KCNH2 | |
| SCHEMBL19834015 | 0.69 | GPR119 (0.51) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656361-B1 | PIPERAZINE WITH OR-SUBSTITUTED PHENYL GROUP AND THEIR USE AS GLYT1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | disclosed |