SCHEMBL504184

SCHEMBL504184

CCCCCCCCCCCCCC=CC(O)C(CO)NC(=O)CCCCCCCCCCCCCCCCC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CETP P11597 4/20 1.00
THRB P10828 1/20 1.00
MEN1 O00255 1/20 1.00
KMT2A Q03164 1/20 1.00
ASAH1 Q13510 2/20 0.78
TP53 P04637 2/20 0.75
CYP1A2 P05177 1/20 0.75
CYP2D6 P10635 1/20 0.75
MAPT P10636 1/20 0.75
CYP2C9 P11712 1/20 0.75
MAPK1 P28482 1/20 0.75
CYP2C19 P33261 1/20 0.75
ASAH2 Q9NR71 2/20 0.71
DEGS1 O15121 1/20 0.70
PLA2G4A P47712 4/20 0.68
ALDH1A1 P00352 2/20 0.64
KDM4E B2RXH2 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4133213 1.00 CETP (1.00) CETPTHRBMEN1KMT2AASAH1
SCHEMBL13863420 1.00 CETP (1.00) CETPTHRBMEN1KMT2AASAH1
SCHEMBL22973496 1.00 CETP (1.00) CETPTHRBMEN1KMT2AASAH1
SCHEMBL5527047 1.00 CETP (1.00) CETPTHRBMEN1KMT2AASAH1
SCHEMBL22911186 1.00 CETP (1.00) CETPTHRBMEN1KMT2AASAH1
SCHEMBL22973426 1.00 CETP (1.00) CETPTHRBMEN1KMT2AASAH1
SCHEMBL24032894 1.00 CETP (1.00) CETPTHRBMEN1KMT2AASAH1
SCHEMBL22973497 1.00 CETP (1.00) CETPTHRBMEN1KMT2AASAH1
SCHEMBL22910831 1.00 CETP (1.00) CETPTHRBMEN1KMT2AASAH1
SCHEMBL22910800 1.00 CETP (1.00) CETPTHRBMEN1KMT2AASAH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116568319-A Method for reversing hepatic steatosis 布莱特西德公司 2023-08-08 CN claimed
US-20120029331-A1 IDENTIFICATION, DIAGNOSIS, AND TREATMENT OF NEUROPATHOLOGIES, NEUROTOXICITIES, TUMORS, AND BRAIN AND SPINAL CORD INJURIES USING ELECTRODES WITH MICROVOLTAMMETRY NEW YORK UNIVERSITY SCHOOL OF MEDICINE (US) 2012-02-02 US claimed
EP-2137204-A1 USE OF SUBSTRATES AS PHARMACOLOGICAL CHAPERONES Amicus Therapeutics, Inc. (US) 2009-12-30 EP claimed
WO-2008128089-A1 USE OF SUBSTRATES AS PHARMACOLOGICAL CHAPERONES AMICUS THERAPEUTICS, INC. (US) 2008-10-23 WO claimed
US-20070026440-A1 Identification, diagnosis, and treatment of neuropathologies, neurotoxicities, tumors, and brain and spinal cord injuries using electrodes with microvoltammetry NEW YORK UNIVERSITY SCHOOL OF MEDICINE 2007-02-01 US claimed
US-6830919-B1 For ceramide metabolism/formation of fatty acid and sphingoid; genetic engineering; for treatment of metabolic disorders TAKARA BIO INC. (JP) 2004-12-14 US claimed
EP-0869185-B9 Production of optically active sphingoid compound SUMITOMO CHEMICAL CO (JP) 2004-08-11 EP claimed
EP-0869185-B1 Production of optically active sphingoid compound SUMITOMO CHEMICAL CO (JP) 2003-09-17 EP claimed
EP-4743440-A1 IONIZABLE LIPIDS eTheRNA immunotherapies NV (BE) 2026-05-20 EP disclosed
EP-4739663-A1 IONIZABLE LIPIDS eTheRNA immunotherapies NV (BE) 2026-05-13 EP disclosed
US-12611419-B2 Liposomal composition for use in a method of treating Parkinson's disease INNOMEDICA HOLDING AG (CH) 2026-04-28 US disclosed
WO-2026047192-A1 IONIZABLE LIPIDS ETHERNA IMMUNOTHERAPIES NV (BE) 2026-03-05 WO disclosed
EP-4680721-A1 BIOPRODUCTION OF GANGLIOSIDES IN RECOMBINANT HOST CELLS Recombia Biosciences, Inc. (US) 2026-01-21 EP disclosed
WO-2025217552-A1 2-(TERT-BUTYL)-4-METHYLPHENYL APPENDED 1,4-DIAZEPANE BASED NOVEL TFEB ACTIVATING COMPOUNDS AS AUTOPHAGY MODULATORS FOR NEURODEGENERATIVE DISORDERS INCLUDING ALZHEIMER'S DISEASE (AD) MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2025-10-16 WO disclosed
WO-2000037046-A1 THERAPEUTIC DELIVERY USING COMPOUNDS SELF-ASSEMBLED INTO HIGH AXIAL RATIO MICROSTRUCTURES UNIVERSITY OF WASHINGTON (US) 2000-06-29 WO disclosed
US-6046040-A Method for producing glycoconjugates TOYO BOSEKI KABUSHIKI KAISHA (JP) 2000-04-04 US disclosed
EP-0940409-A1 PROCESS FOR THE PREPARATION OF SPHINGOLIPIDS AND SPHINGOLIPID DERIVATIVES TAKARA SHUZO CO. LTD. (JP) 1999-09-08 EP disclosed
EP-0897014-A2 Method for producing glycoconjugates Toyo Boseki Kabushiki Kaisha (JP) 1999-02-17 EP disclosed
US-5851536-A Therapeutic delivery using compounds self-assembled into high axial ratio microstructures UNIVERSITY OF WASHINGTON (US) 1998-12-22 US disclosed
EP-0869185-A2 Production of optically active sphingoid compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12611419-B2 Liposomal composition for use in a method of treating Parkinson's disease SMPD2, SMPD1, SGMS2 CETP 194/4885THRB 1059/4885MEN1 345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.