Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | RXRA | P19793 | 1/20 | 0.67 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | RARA | P10276 | 2/20 | 0.59 |
| ▸ | RARB | P10826 | 2/20 | 0.59 |
| ▸ | RARG | P13631 | 2/20 | 0.59 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.58 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.58 |
| ▸ | PLAU | P00749 | 2/20 | 0.57 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | PLG | P00747 | 1/20 | 0.55 |
| ▸ | PLAT | P00750 | 1/20 | 0.55 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5047379 | 0.90 | KDM4E (0.74) | KDM4ERXRACA1CA2RARA | |
| SCHEMBL14284927 | 0.86 | CYP11B1 (0.68) | KDM4EHSD17B1HSD17B2PLAUCYP11B1 | |
| SCHEMBL8132 | 0.85 | KDM4E (1.00) | KDM4ERXRACA1CA2RARA | |
| SCHEMBL34463427 | 0.85 | KDM4E (1.00) | KDM4ERXRACA1CA2RARA | |
| SCHEMBL3008341 | 0.85 | HSD17B1 (0.72) | KDM4ERXRAHSD17B1HSD17B2CYP11B1 | |
| SCHEMBL2043183 | 0.85 | CA1 (0.87) | KDM4ERXRACA1CA2CHEK1 | |
| SCHEMBL15897010 | 0.85 | CYP11B1 (0.69) | KDM4ECA1CA2HSD17B1HSD17B2 | |
| SCHEMBL9702751 | 0.84 | KDM4E (0.77) | KDM4ERXRACA1CA2CYP1A2 | |
| Hydrochloric Acid SCHEMBL3541422 | 0.84 | KDM4E (0.96) | KDM4ERXRACA1CA2RARA | |
| SCHEMBL5875335 | 0.84 | KDM4E (0.96) | KDM4ERXRACA1CA2RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124473-A | Skin disorders; antiinflammatory agents, antiallergens | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1992-06-23 | — | — | US | claimed |
| EP-0210929-B1 | AROMATIC POLYCYCLIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL AND COSMETIC USE | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1992-06-03 | — | — | EP | claimed |
| US-7317066-B2 | Liquid crystal polymers | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2008-01-08 | — | — | US | disclosed |
| US-7317066-B2 | Liquid crystal polymers | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2008-01-08 | — | — | US | disclosed |
| US-7317066-B2 | Liquid crystal polymers | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2008-01-08 | — | — | US | disclosed |
| US-20060293490-A1 | Liquid crystal polymers | BENICEWICZ BRIAN | 2006-12-28 | — | — | US | disclosed |
| US-7148311-B2 | Liquid crystal polymers | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2006-12-12 | — | — | US | disclosed |
| US-20050197483-A1 | Liquid crystal polymers | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2005-09-08 | — | — | US | disclosed |
| WO-2004016673-A1 | LIQUID CRYSTAL POLYMERS | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2004-02-26 | — | — | WO | disclosed |
| US-5686586-A | Polycyclic aromatic derivatives, process for preparing the same and pharmaceutical and cosmetic compositions containing the same | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1997-11-11 | — | — | US | disclosed |
| US-5602104-A | SKIN DISORDERS, CONJUNCTIVE TISSUE DISORDERS, ANTITUMOR AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1997-02-11 | — | — | US | disclosed |
| US-5434180-A | Skin disorders; retinoid activity; rheumatoid psoriasis; | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1995-07-18 | — | — | US | disclosed |
| US-5124473-A | Skin disorders; antiinflammatory agents, antiallergens | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1992-06-23 | — | — | US | disclosed |