Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5042300 | 0.80 | FTO (0.48) | FTONPSR1KMT2ANPC1RAB9A | |
| SCHEMBL17318062 | 0.78 | FTO (0.57) | FTOKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL29908705 | 0.77 | FTO (0.54) | FTOKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL4665594 | 0.77 | FTO (0.54) | FTOKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL12251392 | 0.77 | FTO (0.42) | FTOALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL9008421 | 0.76 | FTO (0.52) | FTONPSR1KMT2AATMALDH1A1 | |
| SCHEMBL24124089 | 0.74 | FTO (0.50) | FTONPSR1KMT2APOLBALDH1A1 | |
| SCHEMBL7522231 | 0.74 | FTO (0.53) | FTOKMT2A | |
| SCHEMBL7520930 | 0.70 | FTO (0.52) | FTOATMLMNAAKR1B1KDM4E | |
| SCHEMBL7525432 | 0.70 | KDM4E (0.34) | FTOATMALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7425320-B2 | Use of guaiol for treating the skin | CIBA SPECIALTY CHEMICALS CORP (US) | 2008-09-16 | — | — | US | disclosed |
| US-20050058610-A1 | Cosmetic mixtures containing ultraviolet radiation absorber and decoloring agents | CIBA SPECIALTY CHEMICALS CORP. | 2005-03-17 | — | — | US | disclosed |
| EP-1432400-A1 | USE OF GUAIOL FOR TREATING THE SKIN | Ciba SC Holding AG (CH) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003024417-A1 | USE OF GUAIOL FOR TREATING THE SKIN | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-03-27 | — | — | WO | disclosed |
| EP-1051410-B1 | BENZO[B]PYRAN DERIVATIVES USEFUL AS EXTERNAL AGENTS FOR THE SKIN | POLA CHEM IND INC (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-6495524-B1 | PREVENTION AND AMELIORATION OF PIGMENTATION; NO ADVERSE INFLUENCES; SAFE | POLA CHEMICAL INDUSTRIES INC. (JP) | 2002-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050058610-A1 | Cosmetic mixtures containing ultraviolet radiation absorber and decoloring agents | TYR, MC1R, UNG | FTO 1161/4885NPSR1 2582/4885KMT2A 3538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.