Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 17/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5043481 | 0.86 | SLC6A9 (0.59) | SLC6A9KCNH2GAALMNATSHR | |
| SCHEMBL5045527 | 0.86 | SLC6A9 (0.85) | SLC6A9KCNH2 | |
| SCHEMBL4420159 | 0.81 | SLC6A9 (0.69) | SLC6A9KCNH2 | |
| SCHEMBL4422681 | 0.81 | SLC6A9 (0.77) | SLC6A9KCNH2 | |
| SCHEMBL5041661 | 0.81 | SLC6A9 (0.67) | SLC6A9KCNH2 | |
| SCHEMBL4427060 | 0.81 | SLC6A9 (0.77) | SLC6A9KCNH2 | |
| SCHEMBL5047534 | 0.80 | SLC6A9 (0.78) | SLC6A9KCNH2 | |
| SCHEMBL3919870 | 0.80 | SLC6A9 (0.62) | SLC6A9KCNH2GAA | |
| SCHEMBL4432731 | 0.80 | SLC6A9 (0.73) | SLC6A9KCNH2 | |
| SCHEMBL28539721 | 0.80 | SLC6A9 (0.65) | SLC6A9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656361-B1 | PIPERAZINE WITH OR-SUBSTITUTED PHENYL GROUP AND THEIR USE AS GLYT1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | disclosed |