Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 17/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4424086 | 0.91 | SLC6A9 (0.61) | SLC6A9KCNH2GAA | |
| SCHEMBL5042007 | 0.88 | SLC6A9 (0.58) | SLC6A9KCNH2GAA | |
| SCHEMBL5043126 | 0.88 | SLC6A9 (0.59) | SLC6A9KCNH2GAA | |
| SCHEMBL4425808 | 0.87 | SLC6A9 (0.52) | SLC6A9KCNH2GAALMNA | |
| SCHEMBL5043057 | 0.86 | SLC6A9 (0.64) | SLC6A9KCNH2GAALMNATSHR | |
| SCHEMBL4424200 | 0.85 | SLC6A9 (0.44) | SLC6A9KCNH2GAA | |
| SCHEMBL5038132 | 0.84 | SLC6A9 (0.59) | SLC6A9KCNH2GAA | |
| SCHEMBL5042339 | 0.83 | SLC6A9 (0.71) | SLC6A9KCNH2 | |
| SCHEMBL4423997 | 0.83 | SLC6A9 (0.71) | SLC6A9KCNH2 | |
| SCHEMBL4424855 | 0.83 | SLC6A9 (0.71) | SLC6A9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656361-B1 | PIPERAZINE WITH OR-SUBSTITUTED PHENYL GROUP AND THEIR USE AS GLYT1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | disclosed |