Toluene

Toluene

SCHEMBL50431

CC(C)O.Cc1ccccc1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.69
ACHE P22303 4/20 0.69
TSHR P16473 2/20 0.69
ALOX12 P18054 2/20 0.69
ADRA2C P18825 2/20 0.44
KDM4E B2RXH2 2/20 0.44
ADRA2A P08913 1/20 0.44
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
HIF1A Q16665 1/20 0.44
ALDH1A1 P00352 2/20 0.42
HPGD P15428 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
CHRM2 P08172 1/20 0.41
ADRA1A P35348 1/20 0.41
RGS12 O14924 1/20 0.41
GLA P06280 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL11305018 0.97 LMNA (0.65) LMNAACHETSHRALOX12ADRA2C
Toluene SCHEMBL6795640 0.97 LMNA (0.65) LMNAACHETSHRALOX12ADRA2C
Toluene SCHEMBL11298633 0.97 LMNA (0.65) LMNAACHETSHRALOX12ADRA2C
Toluene SCHEMBL246259 0.97 LMNA (0.65) LMNAACHETSHRALOX12ADRA2C
Toluene SCHEMBL11305945 0.94 LMNA (0.61) LMNAACHETSHRALOX12ADRA2C
Toluene SCHEMBL8572276 0.92 LMNA (0.58) LMNAACHETSHRALOX12ADRA2C
O-Xylene SCHEMBL29187586 0.92 LMNA (0.58) LMNAACHETSHRALOX12ADRA2C
Toluene SCHEMBL6867152 0.89 LMNA (0.55) LMNAACHETSHRALOX12KDM4E
Toluene SCHEMBL9203170 0.89 LMNA (0.55) LMNAACHETSHRALOX12KDM4E
Toluene SCHEMBL4803839 0.89 LMNA (0.55) LMNAACHETSHRALOX12ADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1577 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118063656-A Dithienopyrrole polymer hole transport material and preparation method and application thereof 南京工业大学 2024-05-24 CN claimed
CN-116573705-B Recycling process of aluminum acid polishing waste liquid 南京大学 2024-01-26 CN claimed
CN-117110507-A Method for improving sensitivity of evaporative light scattering detection of triglyceride components 上海应用技术大学 2023-11-24 CN claimed
CN-114410727-B Preparation method of clavulanone 山东诺明康药物研究院有限公司 2023-09-19 CN claimed
CN-116573705-A Recycling process of aluminum acid polishing waste liquid 南京大学 2023-08-11 CN claimed
CN-116444561-A Preparation method of phosphorothioate compound 浙江理工大学 2023-07-18 CN claimed
CN-111189945-B Separation method of tea aroma components in tea de-enzyming substances of Tieguanyin tea 福建中烟工业有限责任公司 2022-09-30 CN claimed
CN-111175421-B Method for analyzing fruit aroma components in Tieguanyin primary product or Tieguanyin finished product tea 福建中烟工业有限责任公司 2022-08-30 CN claimed
CN-114188092-B Processing technology of special-shaped mica insulation product 浙江荣泰电工器材股份有限公司 2022-06-28 CN claimed
CN-111257477-B Method for simultaneously and quantitatively measuring contents of 41 main aroma components in Tieguanyin tea leaf enzyme-deactivating substance 福建中烟工业有限责任公司 2022-06-21 CN claimed
US-6465799-B1 UV radiation system having materials for selectively attenuating radiation JOHNSON & JOHNSON VISION CARE, INC. 2002-10-15 US claimed
CN-1306864-A Ultraviolet radiation system having material for selectively attenuating radiation JOHNSON & JOHNSON VISION CARE (US) 2001-08-08 CN claimed
CN-1291696-A Reflector for ultraviolet radiation source JOHNSON & JOHNSON VISION CARE (US) 2001-04-18 CN claimed
EP-1069444-A2 UV radiation system having materials for selectively attenuating radiation Johnson & Johnson Vision Care, Inc. (US) 2001-01-17 EP claimed
EP-1069441-A2 Reflectors for UV radiation source Johnson & Johnson Vision Care, Inc. (US) 2001-01-17 EP claimed
EP-0973737-A4 EFFICIENT SYNTHESIS OF A CHIRAL MEDIATOR MERCK & CO INC (US) 2000-04-26 EP claimed
EP-0973737-A1 EFFICIENT SYNTHESIS OF A CHIRAL MEDIATOR Merck & Co., Inc. (US) 2000-01-26 EP claimed
US-5856492-A N-HYDROXYHYDROCARBYL-N-HETEROCYCLE, REVERSE TRANSCRIPTASE INHIBITOR INTERMEDIATE MERCK & CO., INC. (US) 1999-01-05 US claimed
WO-1998030540-A1 EFFICIENT SYNTHESIS OF A CHIRAL MEDIATOR MERCK & CO., INC. (US) 1998-07-16 WO claimed
US-3931116-A CURABLE AMINE-TERMINATED POLYURETHANE-UREA-EPOXIDE LACQUERS WITCO CHEMICAL CORPORATION (US) 1976-01-06 US claimed