Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | ACHE | P22303 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.65 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL27917897 | 0.97 | LMNA (0.69) | LMNAACHETSHRALOX12ADRA2C | |
| Toluene SCHEMBL50431 | 0.97 | LMNA (0.69) | LMNAACHETSHRALOX12ADRA2C | |
| Toluene SCHEMBL28086966 | 0.97 | LMNA (0.69) | LMNAACHETSHRALOX12ADRA2C | |
| Toluene SCHEMBL246259 | 0.94 | LMNA (0.65) | LMNAACHETSHRALOX12ADRA2C | |
| Toluene SCHEMBL11305018 | 0.94 | LMNA (0.65) | LMNAACHETSHRALOX12ADRA2C | |
| Toluene SCHEMBL11298633 | 0.94 | LMNA (0.65) | LMNAACHETSHRALOX12ADRA2C | |
| Toluene SCHEMBL11305945 | 0.92 | LMNA (0.61) | LMNAACHETSHRALOX12ADRA2C | |
| Toluene SCHEMBL8572276 | 0.89 | LMNA (0.58) | LMNAACHETSHRALOX12ADRA2C | |
| O-Xylene SCHEMBL29187586 | 0.89 | LMNA (0.58) | LMNAACHETSHRALOX12ADRA2C | |
| Toluene SCHEMBL27996487 | 0.88 | LMNA (0.50) | LMNAACHETSHRALOX12KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040039206-A1 | Process for resolving racemic mixtures of piperidine derivatives | MOHER ERIC DAVID (US) | 2004-02-26 | — | — | US | disclosed |
| EP-1341762-A1 | PROCESS FOR RESOLVING RACEMIC MIXTURES OF PIPERIDINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002068391-A1 | PROCESS FOR RESOLVING RACEMIC MIXTURES OF PIPERIDINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2002-09-06 | — | — | WO | disclosed |
| WO-1998030650-A1 | ANTISTATIC PEROXIDE COMPOSITION | AKZO NOBEL N.V. (NL) | 1998-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039206-A1 | Process for resolving racemic mixtures of piperidine derivatives | SRR, OPRM1, SRM | LMNA 1605/4885ACHE 660/4885TSHR 2004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.