Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18873597 | 0.91 | THRB (0.55) | TSHRALDH1A1CYP3A4THRBHTT | |
| SCHEMBL17791310 | 0.91 | THRB (0.62) | TSHRALDH1A1CYP3A4THRBHTT | |
| SCHEMBL8088145 | 0.89 | HTT (0.48) | TSHRALDH1A1CYP3A4THRBHTT | |
| SCHEMBL28297899 | 0.89 | THRB (0.60) | TSHRALDH1A1CYP3A4THRBHTT | |
| SCHEMBL5045656 | 0.88 | TSHR (0.56) | TSHRALDH1A1CYP3A4THRBHTT | |
| SCHEMBL26120483 | 0.88 | TSHR (0.56) | TSHRALDH1A1CYP3A4THRBHTT | |
| SCHEMBL19220424 | 0.88 | TSHR (0.56) | TSHRALDH1A1CYP3A4THRBHTT | |
| SCHEMBL20251281 | 0.88 | TSHR (0.56) | TSHRALDH1A1CYP3A4THRBHTT | |
| SCHEMBL12172633 | 0.87 | TSHR (0.63) | TSHRALDH1A1CYP3A4THRBHTT | |
| SCHEMBL13289971 | 0.87 | TSHR (0.63) | TSHRALDH1A1CYP3A4THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7419620-B2 | Dichroic mixtures | ROLIC LTD C/O ROLIC TECHNOLOGIES LTD (CH) | 2008-09-02 | — | — | US | disclosed |
| EP-1385914-B1 | DICHROIC MIXTURE | ROLIC AG (CH) | 2008-07-23 | — | — | EP | disclosed |
| US-20040164272-A1 | Dichoric mixture | ROLIC AG (CH) | 2004-08-26 | — | — | US | disclosed |
| EP-1154981-B1 | LIQUID CRYSTAL COMPOUNDS | ROLIC AG (CH) | 2004-07-21 | — | — | EP | disclosed |
| EP-1385914-A1 | DICHROIC MIXTURE | Rolic AG (CH) | 2004-02-04 | — | — | EP | disclosed |
| US-6676851-B1 | LOW MELTING, GOOD ALIGNMENT ARYL BRANCHED ETHER-ESTER LINKED DIACRYLATES; REMAIN STABLE DURING COATING AND CROSSLINKING | ROLIC AG (CH) | 2004-01-13 | — | — | US | disclosed |
| WO-2002090447-A1 | DICHROIC MIXTURE | ROLIC AG (CH) | 2002-11-14 | — | — | WO | disclosed |
| EP-1256602-A1 | Dichroic mixture | Rolic AG (CH) | 2002-11-13 | — | — | EP | disclosed |
| EP-1154981-A1 | LIQUID CRYSTAL COMPOUNDS | Rolic AG (CH) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000048985-A1 | LIQUID CRYSTAL COMPOUNDS | ROLIC AG (CH) | 2000-08-24 | — | — | WO | disclosed |