Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12172631 | 0.92 | THRB (0.63) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL5043163 | 0.91 | TSHR (0.59) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL17716764 | 0.89 | THRB (0.69) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL12172632 | 0.89 | THRB (0.63) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL14400694 | 0.88 | THRB (0.58) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL13289971 | 0.88 | TSHR (0.63) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL12172633 | 0.88 | TSHR (0.63) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL723159 | 0.88 | TSHR (0.63) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL14907526 | 0.88 | TSHR (0.63) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL16893759 | 0.87 | THRB (0.69) | THRBTSHRHPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10919870-B2 | Polymerizable compound and optically anisotropic body | DIC CORPORATION (JP) | 2021-02-16 | — | — | US | disclosed |
| US-10428032-B2 | Polymerizable compound and optically anisotropic body | DIC CORPORATION (JP) | 2019-10-01 | — | — | US | disclosed |
| US-10253125-B2 | Polymerizable liquid crystal composition and optically anisotropic body, retardation film, and patterned retardation film using the same | DIC CORPORATION (JP) | 2019-04-09 | — | — | US | disclosed |
| US-20170158793-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND OPTICALLY ANISOTROPIC BODY, RETARDATION FILM, AND PATTERNED RETARDATION FILM USING THE SAME | DIC CORPORATION (JP) | 2017-06-08 | — | — | US | disclosed |
| US-20170158793-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND OPTICALLY ANISOTROPIC BODY, RETARDATION FILM, AND PATTERNED RETARDATION FILM USING THE SAME | DIC CORPORATION (JP) | 2017-06-08 | — | — | US | disclosed |
| WO-2017079867-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY | DIC CORPORATION (JP) | 2017-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10919870-B2 | Polymerizable compound and optically anisotropic body | ZYX, ZW10, DPY30 | THRB 4689/4885TSHR 4662/4885HPGD 4284/4885 |
| US-10428032-B2 | Polymerizable compound and optically anisotropic body | CCNY, F12, CCNI | THRB 4837/4885TSHR 4697/4885HPGD 2296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.