SCHEMBL504369

SCHEMBL504369

CCCCCCCCCc1cccc(O)c1OCC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BID P55957 6/20 0.55
MCL1 Q07820 6/20 0.55
BCL2L1 Q07817 5/20 0.55
BAK1 Q16611 5/20 0.55
KAT8 Q9H7Z6 3/20 0.55
SAE1 Q9UBE0 2/20 0.55
EP300 Q09472 2/20 0.55
KAT5 Q92993 2/20 0.55
PPARA Q07869 2/20 0.55
PPARG P37231 1/20 0.55
KAT2A Q92830 1/20 0.55
KAT2B Q92831 1/20 0.55
ALOX5 P09917 2/20 0.50
PTGS2 P35354 1/20 0.50
F7 P08709 3/20 0.48
F3 P13726 3/20 0.48
MMP2 P08253 2/20 0.48
MAPT P10636 2/20 0.48
ALOX15 P16050 2/20 0.48
KDM4E B2RXH2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11659773 1.00 BID (0.55) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL11663551 1.00 BID (0.55) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL10636533 0.98 BID (0.54) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL18263237 0.86 IAPP (0.44) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL15228953 0.85 ALOX5 (0.59) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL27981225 0.85 ALOX5 (0.59) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL28328703 0.85 ALOX5 (0.59) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL6755989 0.82 PTGS2 (0.51) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL981307 0.80 BID (0.55) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL983240 0.80 BID (0.55) BIDMCL1BCL2L1BAK1KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3099654-B1 SYNTHETIC METHOD UNIV COURT UNIV ST ANDREWS (GB) 2018-05-09 EP claimed
US-9908826-B2 Synthetic method UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) 2018-03-06 US claimed
EP-2895452-B1 METATHESIS REACTIONS WITH CARDANOL AND/OR ANACARDIC ACID UNIV COURT UNIV ST ANDREWS (GB) 2017-08-09 EP claimed
US-20170174608-A1 Synthetic Method UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) 2017-06-22 US claimed
US-9670109-B2 Metathesis reactions with cardanol and/or anacardic acid UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) 2017-06-06 US claimed
EP-3099654-A1 SYNTHETIC METHOD University Court of The University of St Andrews (GB) 2016-12-07 EP claimed
CN-106164024-A Synthesis method 圣安德鲁斯大学董事会 2016-11-23 CN claimed
US-20150321981-A1 METATHESIS REACTIONS WITH CARDANOL AND/OR ANACARDIC ACID UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) 2015-11-12 US claimed
WO-2015114323-A1 SYNTHETIC METHOD UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) 2015-08-06 WO claimed
EP-2895452-A1 METATHESIS REACTIONS WITH CARDANOL AND/OR ANACARDIC ACID University Court of The University of St Andrews (GB) 2015-07-22 EP claimed
WO-2014041344-A1 METATHESIS REACTIONS WITH CARDANOL AND/OR ANACARDIC ACID UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) 2014-03-20 WO claimed
US-5444094-A Contacting surface with solution containing quaternary ammonium salt and glycol ether STEPAN COMPANY (US) 1995-08-22 US claimed
EP-3099654-B1 SYNTHETIC METHOD UNIV COURT UNIV ST ANDREWS (GB) 2018-05-09 EP disclosed
US-9908826-B2 Synthetic method UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) 2018-03-06 US disclosed
EP-2895452-B1 METATHESIS REACTIONS WITH CARDANOL AND/OR ANACARDIC ACID UNIV COURT UNIV ST ANDREWS (GB) 2017-08-09 EP disclosed
US-20170174608-A1 Synthetic Method UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) 2017-06-22 US disclosed
WO-2011011878-A1 DRILLING FLUID ADDITIVE COMPRISING AN OIL AND MULTIPLE GUAR COMPOUNDS MASIKEWICH JAMES D (CA) 2011-02-03 WO disclosed
US-5444094-A Contacting surface with solution containing quaternary ammonium salt and glycol ether STEPAN COMPANY (US) 1995-08-22 US disclosed
US-4549884-A Diesel oil containing monoalkoxylated nonyl phenol characterized by decrease in visible smoke in exhaust gases TEXACO INC. (US) 1985-10-29 US disclosed
US-4077917-A SURFACTANTS ALCOLAC, INC. (US) 1978-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150321981-A1 METATHESIS REACTIONS WITH CARDANOL AND/OR ANACARDIC ACID CIAPIN1, C9, C3AR1 BID 1045/4885MCL1 287/4885BCL2L1 131/4885
US-20170174608-A1 Synthetic Method SQLE, FDFT1, CYP51A1 BID 3363/4885MCL1 1354/4885BCL2L1 3642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.