Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | FAAH | O00519 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5039674 | 0.80 | NPC1 (0.68) | RAB9ANPC1FAAHKMT2ALMNA | |
| SCHEMBL5039677 | 0.80 | NPC1 (0.68) | RAB9ANPC1FAAHKMT2ALMNA | |
| SCHEMBL5045742 | 0.78 | NPC1 (0.65) | RAB9ANPC1FAAHKMT2ALMNA | |
| SCHEMBL1858952 | 0.78 | NPC1 (0.62) | RAB9ANPC1FAAHKMT2ALMNA | |
| SCHEMBL11717444 | 0.77 | NPC1 (0.76) | RAB9ANPC1FAAHKMT2ALMNA | |
| SCHEMBL6023305 | 0.76 | MEN1 (0.43) | RAB9ANPC1KMT2AMAPT | |
| SCHEMBL5048692 | 0.76 | MEN1 (0.43) | RAB9ANPC1KMT2AMAPT | |
| SCHEMBL17822164 | 0.75 | NPC1 (1.00) | RAB9ANPC1KMT2ALMNAKLF5 | |
| SCHEMBL30666147 | 0.75 | NPC1 (1.00) | RAB9ANPC1KMT2ALMNAKLF5 | |
| SCHEMBL17892323 | 0.74 | RAB9A (0.59) | RAB9ANPC1FAAHKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | disclosed |