Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.42 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.42 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.42 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6023305 | 1.00 | MEN1 (0.43) | MEN1KMT2ARXFP1POLBPLAAT3 | |
| SCHEMBL5048719 | 0.96 | MEN1 (0.45) | MEN1KMT2APOLBPLAAT3PLAAT5 | |
| SCHEMBL6022081 | 0.94 | MEN1 (0.43) | MEN1KMT2ARXFP1POLBPLAAT3 | |
| SCHEMBL5044952 | 0.94 | MEN1 (0.43) | MEN1KMT2ARXFP1POLBPLAAT3 | |
| SCHEMBL5045311 | 0.91 | GLI1 (0.44) | MEN1KMT2APOLBPLAAT3PLAAT5 | |
| SCHEMBL5044001 | 0.90 | MEN1 (0.42) | MEN1KMT2ARXFP1POLBPLAAT3 | |
| SCHEMBL5043892 | 0.84 | GLI1 (0.43) | MEN1KMT2ARXFP1POLBPLAAT3 | |
| SCHEMBL6022090 | 0.84 | GLI1 (0.43) | MEN1KMT2ARXFP1POLBPLAAT3 | |
| SCHEMBL1857111 | 0.79 | MEN1 (0.45) | MEN1KMT2ARXFP1POLBPLAAT3 | |
| SCHEMBL5043725 | 0.76 | RAB9A (0.58) | KMT2ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | disclosed |