Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 9/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | USP1 | O94782 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5043791 | 0.79 | L3MBTL1 (0.50) | L3MBTL1CREBBPMAPK1PIK3CDALK | |
| SCHEMBL10094327 | 0.74 | L3MBTL1 (0.60) | L3MBTL1CREBBPPIK3CDALKKDM5B | |
| SCHEMBL1368851 | 0.73 | L3MBTL1 (0.55) | L3MBTL1CREBBPMAPK1PIK3CDKDM5B | |
| SCHEMBL10094468 | 0.70 | L3MBTL1 (0.55) | L3MBTL1CREBBPPIK3CDKDM5BMKNK1 | |
| SCHEMBL10094217 | 0.70 | KDR (0.43) | L3MBTL1 | |
| SCHEMBL4784136 | 0.69 | L3MBTL1 (0.60) | L3MBTL1CREBBPMAPK1PIK3CDALK | |
| SCHEMBL2063286 | 0.66 | KCNA5 (0.64) | L3MBTL1CREBBPMAPK1PDK2 | |
| SCHEMBL2695034 | 0.66 | L3MBTL1 (0.46) | L3MBTL1CREBBPMAPK1PIK3CDALK | |
| SCHEMBL10094644 | 0.65 | CREBBP (0.69) | L3MBTL1CREBBPPIK3CDALKPDK2 | |
| SCHEMBL21937939 | 0.65 | CREBBP (0.77) | L3MBTL1CREBBPALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1993551-A2 | POTASSIUM CHANNEL INHIBITORS | Merck & Co., Inc. (US) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007089735-A2 | POTASSIUM CHANNEL INHIBITORS | MERCK & CO., INC. (US) | 2007-08-09 | — | — | WO | disclosed |