Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15158 | 0.89 | LMNA (0.40) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| Iodide SCHEMBL29831346 | 0.87 | LMNA (0.39) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL28286046 | 0.87 | LMNA (0.40) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28310329 | 0.87 | LMNA (0.39) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30988127 | 0.87 | KMT2A (0.41) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL25250816 | 0.87 | LMNA (0.39) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| Hydrogen Sulfide SCHEMBL28313413 | 0.87 | LMNA (0.39) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| Lithium SCHEMBL30307090 | 0.87 | LMNA (0.39) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7180182 | 0.87 | LMNA (0.40) | LMNAKDM4EL3MBTL1TSHRKMT2A | |
| SCHEMBL7180487 | 0.84 | LMNA (0.37) | LMNAL3MBTL1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105884809-A | Preparing method for acyl phosphate (oxide) or sulfonyl phosphate (oxide) compound | 郑成 | 2016-08-24 | — | — | CN | disclosed |
| CN-105884824-A | Preparation method of acyl phosphine (oxygen) or sulfonyl phosphine (oxygen) compounds | 郑成 | 2016-08-24 | — | — | CN | disclosed |
| US-7439401-B2 | Process for preparing acylphosphanes and derivatives thereof | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-10-21 | — | — | US | disclosed |
| US-7439401-B2 | Process for preparing acylphosphanes and derivatives thereof | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-10-21 | — | — | US | disclosed |
| US-7439401-B2 | Process for preparing acylphosphanes and derivatives thereof | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-10-21 | — | — | US | disclosed |
| US-20060247436-A1 | Process for preparing acylphosphanes and derivatives thereof | IGM GROUP B.V. (NL) | 2006-11-02 | — | — | US | disclosed |
| EP-1648908-B1 | PROCESS FOR PREPARING ACYLPHOSPHANES AND DERIVATIVES THEREOF | CIBA SC HOLDING AG (CH) | 2006-10-18 | — | — | EP | disclosed |
| EP-1648908-A1 | PROCESS FOR PREPARING ACYLPHOSPHANES AND DERIVATIVES THEREOF | Ciba SC Holding AG (CH) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005014605-A1 | PROCESS FOR PREPARING ACYLPHOSPHANES AND DERIVATIVES THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247436-A1 | Process for preparing acylphosphanes and derivatives thereof | PHOSPHO1, PLA2G2C, SGMS2 | LMNA 705/4885KDM4E 4208/4885L3MBTL1 3294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.