Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.40 |
| ▸ | HPGD | P15428 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10755284 | 0.87 | KCNH2 (0.42) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL10753255 | 0.84 | ALDH1A1 (0.41) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL10480220 | 0.83 | KCNH2 (0.39) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL5043939 | 0.82 | KDM4E (0.50) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL10757080 | 0.82 | KCNH2 (0.45) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL10480277 | 0.81 | KCNH2 (0.38) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL11106635 | 0.81 | KDM4E (0.39) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL10610892 | 0.80 | KDM4E (0.42) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL11023386 | 0.79 | KCNH2 (0.43) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL10760134 | 0.79 | KDM4E (0.45) | KDM4EHPGDALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0106489-A2 | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1984-04-25 | — | — | EP | disclosed |