Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 10/20 | 0.42 |
| ▸ | NOS1 | P29475 | 9/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 6/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2839205 | 0.85 | NOS2 (0.43) | NOS2NOS1CYP2C9NOS3CNR2 | |
| SCHEMBL4153385 | 0.74 | NOS2 (0.46) | NOS2NOS1CYP2C9NOS3FGFR3 | |
| SCHEMBL2834784 | 0.74 | NOS2 (0.42) | NOS2NOS1CYP2C9NOS3FGFR3 | |
| SCHEMBL5033907 | 0.72 | NOS2 (0.55) | NOS2NOS1CYP2C9NOS3 | |
| SCHEMBL5042184 | 0.72 | KIT (0.42) | NOS2NOS1CYP2C9NOS3 | |
| SCHEMBL4295424 | 0.71 | NOS2 (0.58) | NOS2NOS1CYP2C9NOS3 | |
| SCHEMBL6098288 | 0.71 | NOS2 (0.48) | NOS2NOS1CYP2C9NOS3 | |
| SCHEMBL2831963 | 0.70 | NOS1 (0.40) | NOS2NOS1CYP2C9NOS3CNR2 | |
| SCHEMBL5041158 | 0.70 | NOS2 (0.67) | NOS2NOS1CYP2C9NOS3 | |
| SCHEMBL5037040 | 0.70 | NOS2 (0.57) | NOS2NOS1CYP2C9NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480984-B1 | CONDENSED CAMPTOTHECINS AS ANTITUMOR AGENTS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2008-06-11 | — | — | EP | claimed |