Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 3/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.42 |
| ▸ | ITGAV | P06756 | 3/20 | 0.42 |
| ▸ | RARB | P10826 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044163 | 1.00 | TLR2 (0.42) | TLR2ITGB3ITGAVRARBMEN1 | |
| SCHEMBL3439263 | 0.94 | TLR2 (0.48) | TLR2ITGB3ITGAVPTGS2 | |
| SCHEMBL3439264 | 0.94 | TLR2 (0.48) | TLR2ITGB3ITGAVPTGS2 | |
| SCHEMBL3439075 | 0.93 | ITGB3 (0.48) | TLR2ITGB3ITGAVPTGS2LTB4R2 | |
| SCHEMBL3439074 | 0.93 | ITGB3 (0.48) | TLR2ITGB3ITGAVPTGS2LTB4R2 | |
| SCHEMBL3439066 | 0.92 | TLR2 (0.43) | TLR2ITGB3ITGAVPTGS2 | |
| SCHEMBL3439065 | 0.92 | TLR2 (0.43) | TLR2ITGB3ITGAVPTGS2 | |
| SCHEMBL3439259 | 0.91 | TLR2 (0.42) | TLR2ITGB3ITGAVPTGS2 | |
| SCHEMBL3439258 | 0.91 | TLR2 (0.42) | TLR2ITGB3ITGAVPTGS2 | |
| SCHEMBL3439039 | 0.90 | PTGS2 (0.44) | ITGB3ITGAVPTGS2LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7452878-B2 | Biaromatic compounds which activate PPARγ type receptors and cosmetic/pharmaceutical compositions comprised thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2008-11-18 | — | — | US | claimed |