Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 7/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | TACR2 | P21452 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1855128 | 0.87 | S1PR1 (0.50) | S1PR1S1PR3S1PR2S1PR4PLK1 | |
| SCHEMBL1854388 | 0.87 | S1PR1 (0.50) | S1PR1S1PR3S1PR2S1PR4PLK1 | |
| SCHEMBL1852885 | 0.87 | FFAR1 (0.45) | PLK1FAAHHDAC1HDAC8SLC6A4 | |
| Hydrochloric Acid SCHEMBL1855393 | 0.86 | S1PR1 (0.49) | S1PR1S1PR3S1PR2S1PR4PLK1 | |
| SCHEMBL17225164 | 0.85 | HSD17B10 (0.49) | PLK1HSD17B10TSHRFAAHHDAC1 | |
| SCHEMBL4965818 | 0.82 | S1PR1 (0.43) | S1PR1S1PR3S1PR2S1PR4HDAC1 | |
| SCHEMBL1855408 | 0.80 | SCN5A (0.40) | S1PR1S1PR3S1PR2S1PR4PLK1 | |
| SCHEMBL5044821 | 0.80 | HSD17B10 (0.44) | S1PR1S1PR3S1PR4PLK1HSD17B10 | |
| SCHEMBL5039909 | 0.80 | HSD17B10 (0.44) | S1PR1S1PR3S1PR4PLK1HSD17B10 | |
| SCHEMBL5045143 | 0.79 | PTGES (0.45) | S1PR1S1PR3S1PR2S1PR4PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |