Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 5/20 | 0.39 |
| ▸ | GLB1 | P16278 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3429997 | 0.83 | GBA1 (0.33) | GBA1GLB1 | |
| SCHEMBL20109895 | 0.77 | GBA1 (0.39) | GBA1GLB1GUSB | |
| SCHEMBL14827671 | 0.74 | ALDH1A1 (0.37) | GBA1GLB1PYGL | |
| SCHEMBL17809705 | 0.72 | GBA1 (0.36) | GBA1GLB1GUSB | |
| SCHEMBL16216895 | 0.72 | GBA1 (0.36) | GBA1GLB1GUSB | |
| SCHEMBL19636877 | 0.71 | GBA1 (0.37) | GBA1GLB1PYGLGUSB | |
| SCHEMBL2769503 | 0.71 | GBA1 (0.37) | GBA1GLB1PYGLGUSB | |
| SCHEMBL14968077 | 0.71 | — | — | |
| SCHEMBL21736599 | 0.70 | — | — | |
| SCHEMBL8259911 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613619-B1 | QUINAZOLINE DERIVATIVES FOR TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2008-03-26 | — | — | EP | disclosed |