SCHEMBL5044963

SCHEMBL5044963

Bc1cc(C2C(C#N)=C(N)Oc3c2ccc2ccccc32)cc(OC)c1OC

nearest known ligand 0.89

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MYB P10242 18/20 0.89

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4335346 0.94 MYB (1.00) MYB
SCHEMBL4331540 0.89 MYB (0.87) MYB
SCHEMBL20368759 0.89 MYB (0.90) MYB
SCHEMBL4327922 0.87 MYB (0.83) MYB
SCHEMBL5045402 0.87 MYB (0.67) MYB
SCHEMBL8543671 0.86 MYB (1.00) MYB
SCHEMBL14319090 0.84 MYB (0.62) MYB
SCHEMBL5048596 0.83 MYB (0.62) MYB
SCHEMBL4327653 0.83 MYB (0.75) MYB
SCHEMBL4325696 0.83 MYB (0.78) MYB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012062905-A2 CHROMENE DERIVATIVES AND THEIR ANALOGA AS WNT PATHWAY ANTAGONISTS DEUTSCHES KREBSFORSCHUNGSZENTRUM (DKFZ) (DE) 2012-05-18 WO disclosed
WO-2012062901-A2 CHROMENE DERIVATIVES AND THEIR ANALOGA AS WNT PATHWAY ANTAGONISTS DEUTSCHES KREBSFORSCHUNGSZENTRUM (DKFZ) (DE) 2012-05-18 WO disclosed