Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYB | P10242 | 16/20 | 0.67 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.55 |
| ▸ | TUBB | P07437 | 2/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.55 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.55 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.55 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.55 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.55 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.55 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.55 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.55 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.55 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.55 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4541136 | 0.90 | TUBB4A (0.69) | MYBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5044963 | 0.87 | MYB (0.89) | MYB | |
| SCHEMBL14319090 | 0.82 | MYB (0.62) | MYBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4539906 | 0.81 | TUBB4A (0.65) | MYBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4540411 | 0.81 | TUBB4A (0.72) | MYBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4335346 | 0.80 | MYB (1.00) | MYB | |
| SCHEMBL4537606 | 0.80 | TUBB4A (0.71) | MYBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4535631 | 0.78 | TUBB4A (0.68) | MYBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5045687 | 0.77 | MYB (0.61) | MYBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14319091 | 0.77 | MYB (0.51) | MYBTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012062905-A2 | CHROMENE DERIVATIVES AND THEIR ANALOGA AS WNT PATHWAY ANTAGONISTS | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DKFZ) (DE) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012062901-A2 | CHROMENE DERIVATIVES AND THEIR ANALOGA AS WNT PATHWAY ANTAGONISTS | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DKFZ) (DE) | 2012-05-18 | — | — | WO | disclosed |