Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | MAOA | P21397 | 4/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | DRD5 | P21918 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL59900 | 0.94 | MAPT (0.62) | MAPTCYP3A4KDM4EMAOACHRNA7 | |
| SCHEMBL14481557 | 0.88 | MAPT (0.68) | MAPTCYP3A4KDM4EMAOACHRNA7 | |
| SCHEMBL29924708 | 0.88 | MAPT (0.68) | MAPTCYP3A4KDM4EMAOACHRNA7 | |
| SCHEMBL2594537 | 0.88 | MAPT (0.68) | MAPTCYP3A4KDM4EMAOACHRNA7 | |
| SCHEMBL361694 | 0.85 | MAPT (0.46) | MAPTCYP3A4KDM4EMAOACHRNA7 | |
| SCHEMBL23674495 | 0.84 | CYP3A4 (0.44) | MAPTCYP3A4KDM4EMAOACHRNA7 | |
| SCHEMBL1506609 | 0.84 | HTR2A (0.47) | MAPTCYP3A4KDM4EMAOACHRNA7 | |
| SCHEMBL20231622 | 0.84 | L3MBTL1 (0.48) | MAPTCYP3A4KDM4EMAOACHRNA7 | |
| SCHEMBL10157987 | 0.84 | HTR2C (0.47) | MAPTCYP3A4KDM4EMAOACHRNA7 | |
| SCHEMBL6313527 | 0.84 | MAPT (0.44) | MAPTCYP3A4KDM4EMAOACHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115337913-B | Catechu [9] arene, and preparation method and application thereof | 浙江大学杭州国际科创中心 | 2024-03-22 | — | — | CN | claimed |
| CN-115337913-A | Catechu [9] arene and preparation method and application thereof | 浙江大学杭州国际科创中心 | 2022-11-15 | — | — | CN | claimed |
| CN-102908149-A | Fingerprint showing spray and method for showing fingerprint by using same | WU SHIYU | 2013-02-06 | — | — | CN | claimed |
| CN-115337913-B | Catechu [9] arene, and preparation method and application thereof | 浙江大学杭州国际科创中心 | 2024-03-22 | — | — | CN | disclosed |
| CN-115337913-B | Catechu [9] arene, and preparation method and application thereof | 浙江大学杭州国际科创中心 | 2024-03-22 | — | — | CN | disclosed |
| CN-117229244-A | Orange ketone analogue and application thereof | 中国科学院新疆理化技术研究所 | 2023-12-15 | — | — | CN | disclosed |
| CN-115677635-A | Aurone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2023-02-03 | — | — | CN | disclosed |
| CN-115337913-A | Catechu [9] arene and preparation method and application thereof | 浙江大学杭州国际科创中心 | 2022-11-15 | — | — | CN | disclosed |
| CN-115337913-A | Catechu [9] arene and preparation method and application thereof | 浙江大学杭州国际科创中心 | 2022-11-15 | — | — | CN | disclosed |
| US-10961396-B2 | Methine dyes | LANXESS DEUTSCHLAND GMBH (DE) | 2021-03-30 | — | — | US | disclosed |
| US-20190112485-A1 | NOVEL METHINE DYES | LANXESS DEUTSCHLAND GMBH (DE) | 2019-04-18 | — | — | US | disclosed |
| EP-1660427-A1 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005016862-A1 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORPORATION (JP) | 2005-02-24 | — | — | WO | disclosed |
| US-6482989-B2 | Method for oxidizing alkanes and cycloalkanes with aldehydes in the presence of copper-based catalysts and nitrogen-containing compounds | OSAKA UNIVERSITY (JP) | 2002-11-19 | — | — | US | disclosed |
| US-20020045778-A1 | Method for oxidizing alkanes and cycloalkanes with aldehydes in the presence of copper-based catalysts and nitrogen-containing compounds | OSAKA UNIVERSITY (JP) | 2002-04-18 | — | — | US | disclosed |
| EP-1174410-A2 | Method for oxidizing alkanes and cycloalkanes with oxygen in the presence of aldehydes, copper-based catalysts and nitrogen-containing compounds | OSAKA UNIVERSITY (JP) | 2002-01-23 | — | — | EP | disclosed |
| CN-1156443-A | Benzocycloalkene compound, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-08-06 | — | — | CN | disclosed |
| EP-0534859-A1 | Benzocyclobutyl- or indanyl-alkyl-amino-alkyl substituted 3-benzazepin-2-ones useful in the treatment of cardiovascular diseases | ADIR ET COMPAGNIE (FR) | 1993-03-31 | — | — | EP | disclosed |
| US-4521607-A | HYPOTENSIVE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-06-04 | — | — | US | disclosed |
| EP-0035868-A1 | Bicyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1981-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190112485-A1 | NOVEL METHINE DYES | TET1, TET3, PRMT5 | MAPT 465/4885CYP3A4 907/4885KDM4E 173/4885 |
| US-10961396-B2 | Methine dyes | PNMT, TET1, PRMT5 | MAPT 405/4885CYP3A4 643/4885KDM4E 180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.