Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.57 |
| ▸ | NOS3 | P29474 | 1/20 | 0.55 |
| ▸ | NOS1 | P29475 | 1/20 | 0.55 |
| ▸ | NOS2 | P35228 | 1/20 | 0.55 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9294904 | 0.89 | DPP4 (0.57) | DPP4NOS3NOS1NOS2PRMT5 | |
| SCHEMBL3785259 | 0.85 | DPP4 (0.57) | DPP4NOS3NOS1NOS2PRMT5 | |
| SCHEMBL27867853 | 0.84 | DPP4 (0.52) | DPP4NOS3NOS1NOS2HSD17B3 | |
| SCHEMBL2571211 | 0.81 | TAAR1 (0.48) | DPP4TAAR1 | |
| SCHEMBL8304619 | 0.81 | DPP4 (0.52) | DPP4NOS3NOS1NOS2PRMT5 | |
| SCHEMBL1038044 | 0.79 | DPP4 (0.69) | DPP4NOS3NOS1NOS2HTR7 | |
| SCHEMBL3787422 | 0.78 | DPP4 (0.62) | DPP4NOS3NOS1NOS2HTR7 | |
| SCHEMBL27987589 | 0.76 | DPP4 (0.59) | DPP4NOS3NOS1NOS2TRPA1 | |
| SCHEMBL25106864 | 0.75 | ALDH1A1 (0.41) | NOS3NOS1NOS2TAAR1BACE1 | |
| SCHEMBL25106855 | 0.75 | ALDH1A1 (0.41) | NOS3NOS1NOS2TAAR1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |