Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | NAMPT | P43490 | 2/20 | 0.56 |
| ▸ | MLYCD | O95822 | 1/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5041082 | 0.87 | NAAA (0.60) | NAAAL3MBTL1NAMPTCYP1A2CYP2C9 | |
| SCHEMBL5045529 | 0.87 | TRPV1 (0.60) | NAAAL3MBTL1SMN1; SMN2LMNATMEM97 | |
| SCHEMBL5044615 | 0.87 | TMEM97 (0.60) | NAAAL3MBTL1MLYCDTHRATHRB | |
| SCHEMBL1851280 | 0.86 | NAAA (0.64) | NAAAL3MBTL1NAMPTMLYCDTHRA | |
| SCHEMBL27619596 | 0.85 | NAAA (0.74) | NAAAL3MBTL1NAMPTMLYCDCYP1A2 | |
| SCHEMBL5040097 | 0.84 | NPC1 (0.68) | NAAAL3MBTL1NAMPTMLYCDTHRA | |
| SCHEMBL5044088 | 0.84 | NAAA (0.54) | NAAAL3MBTL1MLYCDTHRATHRB | |
| SCHEMBL29067687 | 0.84 | NAAA (1.00) | NAAAL3MBTL1NAMPTMLYCDTHRA | |
| SCHEMBL10779959 | 0.84 | NAAA (1.00) | NAAAL3MBTL1NAMPTMLYCDTHRA | |
| SCHEMBL3893523 | 0.84 | NAAA (1.00) | NAAAL3MBTL1NAMPTMLYCDTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |