⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5045785 | 0.83 | SCN8A (0.32) | — | |
| SCHEMBL6715363 | 0.83 | CYP3A4 (0.33) | — | |
| SCHEMBL6719380 | 0.81 | ICMT (0.33) | — | |
| SCHEMBL6022105 | 0.81 | FFAR1 (0.32) | — | |
| SCHEMBL5047701 | 0.79 | FFAR1 (0.47) | — | |
| SCHEMBL5046558 | 0.79 | FFAR1 (0.47) | — | |
| SCHEMBL5044417 | 0.79 | FFAR1 (0.47) | — | |
| SCHEMBL1855810 | 0.78 | FFAR1 (0.32) | — | |
| SCHEMBL1852666 | 0.78 | FFAR1 (0.32) | — | |
| SCHEMBL1854543 | 0.77 | FFAR1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |